SCHEMBL28085253

SCHEMBL28085253

CNC(=O)Oc1cccc(CN)c1

nearest known ligand 0.58

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ACHE P22303 13/20 0.54
BCHE P06276 6/20 0.53
LOXL2 Q9Y4K0 1/20 0.51
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29289964 0.98 ACHE (0.55) ACHEBCHELOXL2ALDH1A1
SCHEMBL11798173 0.85 ACHE (0.55) ACHEBCHE
SCHEMBL11715004 0.84 ACHE (0.54) ACHEBCHEALDH1A1
SCHEMBL27605135 0.83 LOXL2 (0.48) ACHEBCHELOXL2
SCHEMBL28425617 0.83 ALOX5 (0.53) ACHEBCHE
SCHEMBL10815679 0.82 ACHE (0.61) ACHEBCHEALDH1A1
SCHEMBL27512135 0.82 ACHE (0.48) ACHE
SCHEMBL2913614 0.81 CYP3A4 (0.58) ACHELOXL2ALDH1A1
Hydrochloric Acid SCHEMBL2903507 0.80 CYP3A4 (0.56) ACHELOXL2ALDH1A1
SCHEMBL27526614 0.80 KMT2A (0.68) ACHELOXL2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108812681-A Pesticidal compositions and methods related thereto 美国陶氏益农公司 2018-11-16 CN claimed
CN-104981160-B Pesticidal compositions and methods related thereto 美国陶氏益农公司 2018-04-20 CN claimed
CN-107072206-A Pesticidal combination and correlation technique 美国陶氏益农公司 2017-08-18 CN claimed
CN-106458860-A Pesticidal compositions and methods related thereto 美国陶氏益农公司 2017-02-22 CN claimed
CN-103281901-B Pesticidal compositions and methods related thereto 陶氏益农公司 2016-12-28 CN claimed
CN-105792651-A Pesticidal compositions and related methods 美国陶氏益农公司 2016-07-20 CN claimed
CN-109863148-A The purposes of fungicide prevention and treatment pomaceous fruit and the brown rot on tone fruit trees before UK-2A 美国陶氏益农公司 2019-06-07 CN disclosed
CN-109843877-A The purposes of fungicide prevention and treatment rice blast before UK-2A 美国陶氏益农公司 2019-06-04 CN disclosed
CN-109843058-A PICOLINAMIDES AS FUNGICIDES 美国陶氏益农公司 2019-06-04 CN disclosed
CN-109843059-A PICOLINAMIDES AS FUNGICIDES 美国陶氏益农公司 2019-06-04 CN disclosed
CN-105732580-B Pesticidal compositions and methods related thereto 陶氏益农公司 2018-12-07 CN disclosed
CN-107426999-A Picolinamide compound with Fungicidally active 美国陶氏益农公司 2017-12-01 CN disclosed
CN-107427000-A Use of pyridine amide compounds with fungicidal activity 美国陶氏益农公司 2017-12-01 CN disclosed
CN-107205405-A Pyridine amide compounds having fungicidal activity 美国陶氏益农公司 2017-09-26 CN disclosed
CN-106977462-A 5 fluorine, 4 imino group 3 (substituted) 3,4 dihydro-pyrimidin 2 (1H) ketone derivatives 阿达玛马克西姆股份有限公司 2017-07-25 CN disclosed
CN-106458783-A Microencapsulated nitrification inhibitor composition 美国陶氏益农公司 2017-02-22 CN disclosed
CN-106061257-A Use of macrocyclic picolinamides as fungicides 美国陶氏益农公司 2016-10-26 CN disclosed
CN-106061256-A Macrocyclic picolinamide compounds having fungicidal activity 美国陶氏益农公司 2016-10-26 CN disclosed
CN-106028814-A Use of macrocyclic picolinamides as fungicides 美国陶氏益农公司 2016-10-12 CN disclosed
CN-106028815-A Macrocyclic picolinamides as fungicides 美国陶氏益农公司 2016-10-12 CN disclosed