Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.43 |
| ▸ | DRD3 | P35462 | 4/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | LDHB | P07195 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | BID | P55957 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL28176922 | 0.94 | BID (0.47) | DRD2OPRM1DRD3OPRD1OPRK1 | |
| SCHEMBL8095518 | 0.92 | TLR8 (0.44) | LMNAHTTLDHALDHBTLR8 | |
| Phenol SCHEMBL28842124 | 0.91 | TYR (0.46) | DRD2OPRM1DRD3OPRD1OPRK1 | |
| SCHEMBL8095162 | 0.87 | TLR8 (0.49) | TLR8BCL2L1BIDMCL1BAK1 | |
| Phenol SCHEMBL28320910 | 0.86 | TYR (0.42) | DRD2OPRM1DRD3OPRD1OPRK1 | |
| SCHEMBL8102396 | 0.86 | LIPG (0.49) | TLR8BCL2L1BIDMCL1BAK1 | |
| SCHEMBL8100321 | 0.86 | LIPG (0.49) | TLR8BCL2L1BIDMCL1BAK1 | |
| SCHEMBL8087327 | 0.86 | LIPG (0.49) | TLR8BCL2L1BIDMCL1BAK1 | |
| SCHEMBL9845810 | 0.84 | BCL2L1 (0.46) | KEAP1LMNAHTTLDHALDHB | |
| SCHEMBL8087736 | 0.82 | TLR8 (0.43) | LMNAHTTTLR8BCL2L1BID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103553972-B | Method for the preparation of n-substituted carbamic acid ester and method for the preparation of isocyanate using the n-substituted carbamic acid ester | 旭化成株式会社 | 2017-04-12 | — | — | CN | disclosed |
| CN-103588680-B | N-substituted carbamate conveying with and storage compositions and manufacture isocyanates method | 旭化成株式会社 | 2016-08-10 | — | — | CN | disclosed |