SCHEMBL28085384

SCHEMBL28085384

CC(=O)CCc1ccccc1N1CCCCC1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.47
FABP3 P05413 1/20 0.47
FABP4 P15090 1/20 0.47
LIPG Q9Y5X9 2/20 0.45
ALDH1A1 P00352 2/20 0.45
LMNA P02545 1/20 0.45
IAPP P10997 1/20 0.45
GAA P10253 4/20 0.44
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
NCF1 P14598 1/20 0.43
GFER P55789 1/20 0.43
KCNQ2 O43526 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2555538 0.86 FABP3 (0.54) NPC1FABP3FABP4LIPGALDH1A1
SCHEMBL29956353 0.86 FABP3 (0.54) NPC1FABP3FABP4LIPGALDH1A1
SCHEMBL5269342 0.85 SMN1; SMN2 (0.48) ALDH1A1LMNAIAPPKMT2AMEN1
SCHEMBL15330885 0.84 FABP3 (0.52) NPC1FABP3FABP4LIPGGAA
SCHEMBL6514775 0.79 KEAP1 (0.53) NPC1FABP3FABP4LIPGGAA
SCHEMBL11020859 0.79 GAA (0.44) NPC1FABP3FABP4LIPGALDH1A1
Ammonia Solution, Strong SCHEMBL7896018 0.78 KEAP1 (0.52) NPC1FABP3FABP4LIPGGAA
Hydrochloric Acid SCHEMBL29156848 0.78 KEAP1 (0.52) NPC1FABP3FABP4LIPGGAA
SCHEMBL8776692 0.77 NCF1 (0.54) NPC1FABP3FABP4LIPGALDH1A1
SCHEMBL12394615 0.77 THRA (0.41) NPC1FABP3FABP4ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103483295-B Prepare method and the purposes of products made thereby of 3-methyl isophthalic acid-[2-(1-piperidyl) phenyl] fourth imines 河北科技大学 2016-08-17 CN disclosed