Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.61 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.61 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14937230 | 0.83 | KMT2A (0.72) | KMT2AALDH1A1KDM4ETHRBL3MBTL1 | |
| SCHEMBL25438436 | 0.82 | KMT2A (0.63) | KMT2AALDH1A1GAAKDM4ETHRB | |
| SCHEMBL5083625 | 0.80 | KMT2A (0.77) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL28115079 | 0.78 | KMT2A (0.68) | KMT2AALDH1A1L3MBTL1LMNATDP1 | |
| SCHEMBL31525022 | 0.76 | L3MBTL1 (0.63) | KMT2AALDH1A1KDM4ETHRBL3MBTL1 | |
| SCHEMBL1043015 | 0.76 | ALDH1A1 (0.73) | ALDH1A1GAAKDM4ETHRBLMNA | |
| SCHEMBL31006272 | 0.76 | KMT2A (1.00) | KMT2AALDH1A1KDM4ETHRBLMNA | |
| SCHEMBL28108744 | 0.75 | ALDH1A1 (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL10664827 | 0.75 | KDM4E (0.64) | KMT2AALDH1A1GAAKDM4ETHRB | |
| SCHEMBL31326709 | 0.75 | KDM4E (0.64) | KMT2AALDH1A1GAAKDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102947305-B | Compounds and methods for kinase modulation and indications therefor | 普莱希科公司 | 2016-07-06 | — | — | CN | disclosed |