Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28832577 | 0.87 | ESR1 (0.65) | ESR1MAOBALDH1A1HPGDHTT | |
| SCHEMBL28085548 | 0.86 | ESR1 (0.73) | ESR1ALDH1A1HTTKDM4ERAB9A | |
| SCHEMBL28085534 | 0.85 | ESR1 (0.57) | ESR1MAOB | |
| SCHEMBL28085545 | 0.84 | MAOB (0.58) | ESR1MAOBALDH1A1HPGDHTT | |
| SCHEMBL28085701 | 0.80 | MAOB (0.56) | ESR1MAOBALDH1A1HPGDKDM4E | |
| SCHEMBL28085657 | 0.77 | MAOB (0.52) | ESR1MAOBALDH1A1HPGDKDM4E | |
| SCHEMBL31511411 | 0.75 | MAOB (0.67) | MAOBALDH1A1HPGDKDM4ERAB9A | |
| SCHEMBL7117054 | 0.73 | MAOB (0.72) | MAOBALDH1A1HPGDHTTKDM4E | |
| SCHEMBL31511409 | 0.73 | MAOB (0.72) | MAOBALDH1A1HPGDKDM4ERAB9A | |
| SCHEMBL7463411 | 0.73 | MAOB (0.72) | MAOBALDH1A1HPGDKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105801544-A | 3-aryl-4-arylamine-coumarin derivative and preparing method and medical application thereof | 中国药科大学 | 2016-07-27 | — | — | CN | disclosed |