Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18066374 | 0.89 | PTPN1 (0.51) | AKR1C3NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL28205234 | 0.87 | MTNR1A (0.56) | AKR1C3NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL15547831 | 0.85 | ALOX15 (0.53) | SMN1; SMN2KMT2ALMNAALOX15 | |
| SCHEMBL18066371 | 0.84 | PTPN1 (0.51) | AKR1C3PTGESALOX5PPARGMAOB | |
| SCHEMBL27539388 | 0.82 | KDM4E (0.57) | NPC1RAB9ASMN1; SMN2HPGDKMT2A | |
| SCHEMBL10799614 | 0.82 | NPC1 (0.57) | NPC1RAB9ASMN1; SMN2HPGDMTNR1A | |
| SCHEMBL28085736 | 0.82 | ALOX15 (0.54) | AKR1C3NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL3804975 | 0.81 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2HPGDKDM4E | |
| SCHEMBL28085586 | 0.81 | AKR1C3 (0.54) | AKR1C3NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL15556821 | 0.80 | ALOX15 (0.53) | SMN1; SMN2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476676-A | Optical activity pyrans and chromene base phenol derivatives and the pharmaceutical composition comprising it | 格拉斯如睦株式会社 | 2019-03-15 | — | — | CN | disclosed |
| CN-105849111-B | Pyrans and the different cresol derivatives of baynide fibre and metabolic syndrome or treatment of inflammatory diseases pharmaceutical composition | 格拉斯如睦株式会社 | 2018-05-04 | — | — | CN | disclosed |
| CN-105849111-A | Pyranochromenyl phenol derivative, and pharmaceutical composition for treating metabolic syndrome or inflammatory disease | 依如睦生物科技株式会社 | 2016-08-10 | — | — | CN | disclosed |