Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 9/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3804975 | 0.87 | NPC1 (0.54) | MRGPRX4NPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL2776298 | 0.86 | PTPN1 (0.56) | AKR1C3FFAR1FFAR4MRGPRX4NPC1 | |
| SCHEMBL28085736 | 0.85 | ALOX15 (0.54) | AKR1C3FFAR1FFAR4NPC1HPGD | |
| SCHEMBL28238348 | 0.83 | FFAR1 (0.55) | AKR1C3FFAR1FFAR4MRGPRX4NPC1 | |
| SCHEMBL28205234 | 0.83 | MTNR1A (0.56) | AKR1C3MRGPRX4NPC1HPGDRAB9A | |
| SCHEMBL18066391 | 0.82 | FFAR4 (0.50) | AKR1C3FFAR4MRGPRX4NPC1HPGD | |
| SCHEMBL28085690 | 0.81 | AKR1C3 (0.48) | AKR1C3FFAR1NPC1HPGDRAB9A | |
| SCHEMBL23582260 | 0.80 | HTR1A (0.59) | FFAR1FFAR4MRGPRX4NPC1HPGD | |
| SCHEMBL29914010 | 0.80 | HTR1A (0.59) | FFAR1FFAR4MRGPRX4NPC1HPGD | |
| SCHEMBL28085688 | 0.80 | MTNR1A (0.55) | AKR1C3FFAR1FFAR4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105849111-B | Pyrans and the different cresol derivatives of baynide fibre and metabolic syndrome or treatment of inflammatory diseases pharmaceutical composition | 格拉斯如睦株式会社 | 2018-05-04 | — | — | CN | disclosed |
| CN-105849111-A | Pyranochromenyl phenol derivative, and pharmaceutical composition for treating metabolic syndrome or inflammatory disease | 依如睦生物科技株式会社 | 2016-08-10 | — | — | CN | disclosed |