SCHEMBL2808608

SCHEMBL2808608

CC(=COc1ccc(Oc2ccccc2)cc1)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.48
PARP10 Q53GL7 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.45
SRD5A2 P31213 2/20 0.45
HPGD P15428 2/20 0.45
AKR1C3 P42330 1/20 0.44
RAB9A P51151 3/20 0.44
NPC1 O15118 2/20 0.44
ALDH1A1 P00352 2/20 0.44
MEN1 O00255 1/20 0.44
LMNA P02545 1/20 0.44
KMT2A Q03164 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
POLB P06746 1/20 0.44
HSP90AA1 P07900 1/20 0.44
LTA4H P09960 3/20 0.44
NR1H2 P55055 1/20 0.44
BAX Q07812 1/20 0.44
ERCC5 P28715 1/20 0.44
FEN1 P39748 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2808603 1.00 RECQL (0.48) RECQLPARP10SMN1; SMN2SRD5A2HPGD
SCHEMBL156818 0.93 AKR1C3 (0.50) RECQLAKR1C3ALDH1A1MEN1KMT2A
SCHEMBL821031 0.93 AKR1C3 (0.50) RECQLAKR1C3ALDH1A1MEN1KMT2A
SCHEMBL2808841 0.86 GAA (0.46) SMN1; SMN2AKR1C3RAB9ANPC1LMNA
Methacrylic Acid SCHEMBL22264525 0.86 AKR1C3 (0.44) RECQLSMN1; SMN2HPGDAKR1C3ALDH1A1
SCHEMBL2808835 0.86 GAA (0.46) SMN1; SMN2AKR1C3RAB9ANPC1LMNA
SCHEMBL2811454 0.81 LMNA (0.48) SMN1; SMN2HPGDAKR1C3ALDH1A1MEN1
SCHEMBL219559 0.81 AKR1C3 (0.38) PARP10AKR1C3RAB9AALDH1A1MEN1
SCHEMBL2808572 0.81 CA1 (0.48) PARP10HPGDRAB9AALDH1A1MEN1
SCHEMBL2581335 0.81 AKR1C3 (0.38) PARP10AKR1C3RAB9AALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8278473-B2 Alpha, beta-unsaturated imidate compound and pesticidal composition containing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-02 US disclosed
US-20100240729-A1 ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-09-23 US disclosed
WO-2009064031-A1 ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100240729-A1 ALPHA, BETA-UNSATURATED IMIDATE COMPOUND AND PESTICIDAL COMPOSITION CONTAINING THE SAME OXER1, CBR1, DEGS1 RECQL 2329/4885PARP10 4434/4885SMN1; SMN2 1135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.