Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
| ▸ | SIGMAR1 | Q99720 | 18/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Clobenzorex SCHEMBL31080692 | 0.89 | LMNA (1.00) | LMNASIGMAR1POLBMAPK1 | |
| Clobenzorex SCHEMBL26720 | 0.89 | LMNA (1.00) | LMNASIGMAR1POLBMAPK1 | |
| Clobenzorex SCHEMBL1649957 | 0.86 | LMNA (0.94) | LMNASIGMAR1POLBMAPK1 | |
| Mefenorex SCHEMBL149720 | 0.86 | SIGMAR1 (0.72) | SIGMAR1 | |
| Mefenorex SCHEMBL122442 | 0.84 | SIGMAR1 (0.70) | SIGMAR1 | |
| Mefenorex SCHEMBL161841 | 0.83 | SIGMAR1 (0.68) | SIGMAR1 | |
| Clobenzorex SCHEMBL13724087 | 0.77 | LMNA (0.75) | LMNASIGMAR1POLBMAPK1 | |
| SCHEMBL30384619 | 0.76 | SIGMAR1 (0.86) | SIGMAR1 | |
| SCHEMBL13479679 | 0.76 | LMNA (0.74) | LMNASIGMAR1POLBMAPK1 | |
| SCHEMBL20689714 | 0.75 | SIGMAR1 (0.86) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103717597-B | Heterocyclic compounds as kinase inhibitors | 原真股份有限公司 | 2017-07-04 | — | — | CN | disclosed |
| CN-103492389-B | Pyrazolo [4,3-d] pyrimidine as inhibitors of kinases | 原真股份有限公司 | 2016-09-14 | — | — | CN | disclosed |