Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 10/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fenpiverinium SCHEMBL1650132 | 0.86 | CHRM3 (0.55) | OPRM1DRD3DRD2CHRM3CHRM2 | |
| Buzepide SCHEMBL3498775 | 0.85 | CHRM3 (0.57) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| Fenpiverinium SCHEMBL23654 | 0.85 | CHRM3 (0.53) | CHRM3CHRM2CHRM1CHRM4CHRM5 | |
| Iodide SCHEMBL29558329 | 0.66 | CHRM2 (0.83) | OPRM1DRD3DRD2CHRM3CHRM2 | |
| SCHEMBL9295790 | 0.63 | CHRM3 (0.59) | OPRM1DRD3DRD2CHRM3CHRM2 | |
| SCHEMBL3900689 | 0.63 | OPRM1 (0.58) | OPRM1DRD3DRD2CHRM3CHRM2 | |
| SCHEMBL9426731 | 0.62 | OPRM1 (0.54) | OPRM1DRD3DRD2CHRM3CHRM2 | |
| Normethadone SCHEMBL24337 | 0.62 | OPRM1 (1.00) | OPRM1DRD3DRD2CHRM3CHRM2 | |
| Benzene SCHEMBL9326315 | 0.62 | HRH1 (0.39) | OPRM1DRD3DRD2CHRM3CHRM2 | |
| SCHEMBL13541547 | 0.62 | KCNH2 (0.74) | OPRM1DRD3DRD2CHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103717597-B | Heterocyclic compounds as kinase inhibitors | 原真股份有限公司 | 2017-07-04 | — | — | CN | disclosed |
| CN-103492389-B | Pyrazolo [4,3-d] pyrimidine as inhibitors of kinases | 原真股份有限公司 | 2016-09-14 | — | — | CN | disclosed |