Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 5/20 | 0.44 |
| ▸ | BCHE | P06276 | 4/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | NCK1 | P16333 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5456804 | 0.81 | BACE1 (0.55) | LMNAACHEBCHEGRIN1GRIN2A | |
| SCHEMBL438604 | 0.81 | NCF1 (0.63) | LMNANCF1ALDH1A1CASP1CASP7 | |
| SCHEMBL20247527 | 0.81 | KMT2A (0.51) | LMNAACHEBCHEGRIN1GRIN2A | |
| SCHEMBL27588454 | 0.77 | HSD17B10 (0.49) | LMNAACHEBCHEGRIN1GRIN2A | |
| SCHEMBL8234615 | 0.77 | ADRB2 (0.55) | LMNAACHEBCHEGRIN1GRIN2A | |
| SCHEMBL27293402 | 0.75 | NCF1 (0.60) | LMNAACHESMN1; SMN2POLBHTT | |
| SCHEMBL8150490 | 0.71 | ALDH1A1 (0.47) | LMNAACHESMN1; SMN2NCK1BACE1 | |
| SCHEMBL439684 | 0.70 | NCF1 (0.59) | ACHEBCHEGRIN1GRIN2ANCF1 | |
| SCHEMBL8306581 | 0.69 | NR4A2 (0.61) | LMNASMN1; SMN2HTTHIF1ANCK1 | |
| SCHEMBL6679745 | 0.69 | HRH4 (0.58) | HRH4ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103717589-B | For treating or prevent the compound of respiratory syncytial virus disease | 弗·哈夫曼-拉罗切有限公司 | 2016-08-17 | — | — | CN | disclosed |