Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
| ▸ | SCN1A | P35498 | 1/20 | 0.55 |
| ▸ | SCN4A | P35499 | 1/20 | 0.55 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.55 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.55 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.55 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.55 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.55 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.55 |
| ▸ | SCN11A | Q9UI33 | 1/20 | 0.55 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.55 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.53 |
| ▸ | GALR3 | O60755 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cifenline SCHEMBL23712274 | 0.74 | CACNA1F (1.00) | CACNA1FARPDE4ASCN1ASCN4A | |
| Cifenline SCHEMBL122806 | 0.74 | CACNA1F (1.00) | CACNA1FARPDE4ASCN1ASCN4A | |
| Cifenline SCHEMBL23712302 | 0.74 | CACNA1F (1.00) | CACNA1FARPDE4ASCN1ASCN4A | |
| Etilefrine SCHEMBL30510958 | 0.73 | HIF1A (1.00) | LMNAHIF1AGALR3SLC16A3MEN1 | |
| Etilefrine SCHEMBL150802 | 0.73 | HIF1A (1.00) | LMNAHIF1AGALR3SLC16A3MEN1 | |
| Etilefrine SCHEMBL29603739 | 0.73 | HIF1A (1.00) | LMNAHIF1AGALR3SLC16A3MEN1 | |
| Etilefrine SCHEMBL31204243 | 0.71 | HIF1A (0.97) | LMNAHIF1AGALR3SLC16A3MEN1 | |
| Etilefrine SCHEMBL207591 | 0.71 | HIF1A (0.97) | LMNAHIF1AGALR3SLC16A3MEN1 | |
| Cifenline SCHEMBL121044 | 0.70 | CACNA1F (0.79) | CACNA1FARPDE4ASCN1ASCN4A | |
| Etilefrine SCHEMBL10753730 | 0.67 | HIF1A (0.78) | LMNAHIF1AGALR3SLC16A3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103717597-B | Heterocyclic compounds as kinase inhibitors | 原真股份有限公司 | 2017-07-04 | — | — | CN | disclosed |
| CN-103492389-B | Pyrazolo [4,3-d] pyrimidine as inhibitors of kinases | 原真股份有限公司 | 2016-09-14 | — | — | CN | disclosed |