Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.71 |
| ▸ | HTT | P42858 | 6/20 | 0.71 |
| ▸ | MAPT | P10636 | 5/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.71 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 4/20 | 0.71 |
| ▸ | TP53 | P04637 | 3/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.71 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.71 |
| ▸ | MMP14 | P50281 | 3/20 | 0.71 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.71 |
| ▸ | USP2 | O75604 | 2/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684999 | 0.85 | MAPT (0.73) | MEN1KMT2AKDM4EHTTMAPT | |
| Clioquinol SCHEMBL11749381 | 0.84 | KDM4E (1.00) | MEN1KMT2AKDM4EHTTMAPT | |
| Clioquinol SCHEMBL30592904 | 0.84 | KDM4E (1.00) | MEN1KMT2AKDM4EHTTMAPT | |
| Clioquinol SCHEMBL29370380 | 0.84 | KDM4E (1.00) | MEN1KMT2AKDM4EHTTMAPT | |
| Clioquinol SCHEMBL3967 | 0.84 | KDM4E (1.00) | MEN1KMT2AKDM4EHTTMAPT | |
| Chlorquinaldol SCHEMBL7646087 | 0.84 | MAPT (0.68) | MEN1KMT2AKDM4EHTTMAPT | |
| Chloroxine SCHEMBL29157288 | 0.83 | KDM4E (0.80) | MEN1KMT2AKDM4EHTTMAPT | |
| Clioquinol SCHEMBL18985133 | 0.83 | KDM4E (0.97) | MEN1KMT2AKDM4EHTTMAPT | |
| Clioquinol SCHEMBL28531298 | 0.83 | KDM4E (0.97) | MEN1KMT2AKDM4EHTTMAPT | |
| Clioquinol SCHEMBL28529781 | 0.83 | KDM4E (0.97) | MEN1KMT2AKDM4EHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103492389-B | Pyrazolo [4,3-d] pyrimidine as inhibitors of kinases | 原真股份有限公司 | 2016-09-14 | — | — | CN | disclosed |