Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | EED | O75530 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL818434 | 0.83 | GBA1 (0.51) | GBA1SLC6A4 | |
| SCHEMBL9950572 | 0.83 | SRC (0.46) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL9950949 | 0.80 | MEN1 (0.39) | SLC6A4MEN1LMNATHRBBLM | |
| SCHEMBL9949665 | 0.80 | MEN1 (0.39) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL9949655 | 0.78 | LMNA (0.36) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL817622 | 0.74 | EED (0.45) | GBA1SLC6A4EEDMAOB | |
| SCHEMBL25173673 | 0.74 | SLC6A4 (0.58) | GBA1SLC6A4MAOA | |
| SCHEMBL3966077 | 0.74 | GBA1 (0.56) | GBA1SLC6A4LMNA | |
| SCHEMBL6383375 | 0.74 | GBA1 (0.56) | GBA1SLC6A4 | |
| SCHEMBL21800055 | 0.74 | GBA1 (0.56) | GBA1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104039789-B | Four azepines-cyclopenta [a] indenyl and the purposes as forward allosteric modulators thereof | 默克专利股份有限公司 | 2016-09-07 | — | — | CN | disclosed |