Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 4/20 | 0.37 |
| ▸ | CHRM1 known ✓ | P11229 | 4/20 | 0.37 |
| ▸ | CHRM3 known ✓ | P20309 | 4/20 | 0.37 |
| ▸ | ADRA2A known ✓ | P08913 | 2/20 | 0.37 |
| ▸ | ADRA2B known ✓ | P18089 | 2/20 | 0.37 |
| ▸ | ADRA2C known ✓ | P18825 | 2/20 | 0.37 |
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.37 |
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 known ✓ | P08588 | 1/20 | 0.37 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.37 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.37 |
| ▸ | OPRK1 known ✓ | P41145 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL2793232 | 0.99 | THRB (0.47) | THRBDNM1MEN1KMT2ATP53 | |
| Sulfuric Acid SCHEMBL2976040 | 0.94 | THRB (0.45) | THRBDNM1MEN1KMT2ATP53 | |
| SCHEMBL1476296 | 0.93 | THRB (0.51) | THRBDNM1MEN1KMT2ATP53 | |
| Sulfuric Acid SCHEMBL2793229 | 0.92 | THRB (0.46) | THRBDNM1MEN1KMT2ATP53 | |
| Iodide SCHEMBL2252610 | 0.92 | THRB (0.50) | THRBDNM1MEN1KMT2ATP53 | |
| Hydrochloric Acid SCHEMBL543368 | 0.92 | THRB (0.50) | THRBDNM1MEN1KMT2ATP53 | |
| Fluoride Ion SCHEMBL28527581 | 0.92 | THRB (0.50) | THRBDNM1MEN1KMT2ATP53 | |
| Bromide SCHEMBL2252458 | 0.92 | THRB (0.50) | THRBDNM1MEN1KMT2ATP53 | |
| Trifluoromethanesulfonic Acid SCHEMBL16108555 | 0.90 | THRB (0.42) | THRBDNM1MEN1KMT2ATP53 | |
| Sulfuric Acid SCHEMBL28988171 | 0.90 | DNM1 (0.46) | THRBDNM1MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102304206-B | The method preparing the dispersion of polymer particle of surfactant-free insensitive for pH in aqueous medium | 阿科玛股份有限公司 | 2016-08-10 | — | — | CN | disclosed |