Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28832682 | 0.86 | HPGD (0.41) | CARM1PRMT6BCHESMN1; SMN2 | |
| SCHEMBL6424545 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2POLB | |
| SCHEMBL28086939 | 0.80 | BCHE (0.47) | CARM1PRMT6BCHESMN1; SMN2SIGMAR1 | |
| SCHEMBL28751511 | 0.78 | EPHX2 (0.49) | POLBL3MBTL1HTR2CSLC6A4EPHX2 | |
| SCHEMBL28943532 | 0.77 | PNMT (0.43) | KDM4ESMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL27638858 | 0.76 | CARM1 (0.50) | CARM1PRMT6BCHESIGMAR1 | |
| SCHEMBL27787081 | 0.72 | POLB (0.47) | POLBEPHX2 | |
| SCHEMBL6424398 | 0.72 | HTR2C (0.51) | CARM1PRMT6HTR2CHTR2BSLC6A4 | |
| SCHEMBL27658735 | 0.71 | LIPC (0.36) | — | |
| SCHEMBL28078742 | 0.71 | FPR2 (0.51) | SMN1; SMN2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104520292-B | Sulphonylpiperidine derivant and they are for treating the purposes of disease of front dynein mediation | 武田药品工业株式会社 | 2016-09-14 | — | — | CN | disclosed |