Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.37 |
| ▸ | HTR2C | P28335 | 4/20 | 0.37 |
| ▸ | HTR2B | P41595 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5543056 | 0.85 | SLC6A4 (0.46) | HRH1SLC6A4HTR2CHTR2BSLC6A2 | |
| SCHEMBL5542018 | 0.77 | SLC6A2 (0.44) | HRH1SLC6A4HTR2CHTR2BSLC6A2 | |
| Tert-Butyl Formate SCHEMBL27658738 | 0.76 | TDP1 (0.39) | SLC6A4HTR2CHTR2BSLC6A2SLC6A3 | |
| Tert-Butyl Formate SCHEMBL28096252 | 0.75 | HTR3A (0.53) | HTR2CHTR3AHTR6 | |
| Tert-Butyl Formate SCHEMBL28078854 | 0.74 | TDP1 (0.43) | SLC6A4HTR2CHTR2BSLC6A2SLC6A3 | |
| Tert-Butyl Formate SCHEMBL28087005 | 0.74 | SLC6A4 (0.40) | SLC6A4HTR2CHTR2BSLC6A2SLC6A3 | |
| Tert-Butyl Formate SCHEMBL28793707 | 0.73 | HRH1 (0.48) | HRH1ITGB3ITGA2BPPARA | |
| Tert-Butyl Formate SCHEMBL27993846 | 0.73 | CXCR4 (0.48) | — | |
| Tert-Butyl Formate SCHEMBL28078907 | 0.72 | HRH1 (0.43) | HRH1SLC6A4HTR2CHTR2B | |
| Tert-Butyl Formate SCHEMBL27615609 | 0.71 | SLC6A4 (0.38) | SSTR4SLC6A4SLC6A2SLC6A3REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104520292-B | Sulphonylpiperidine derivant and they are for treating the purposes of disease of front dynein mediation | 武田药品工业株式会社 | 2016-09-14 | — | — | CN | disclosed |