Tetrahydrofuran

Tetrahydrofuran

SCHEMBL2148282

C1CCOC1.c1cc[nH]c1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrrole SCHEMBL27352233 0.97 ALDH1A1 (0.47) ALDH1A1
Pyrrole SCHEMBL28200279 0.94 ALDH1A1 (0.44) ALDH1A1
Dioxane SCHEMBL28087350 0.87 TTR (0.43) ALDH1A1
Pyrrole SCHEMBL18339868 0.83
Pyrrole SCHEMBL29867603 0.80
Morpholine SCHEMBL9049013 0.77 MEN1 (0.58)
Benzene SCHEMBL1051803 0.75 ALDH1A1 (0.73) ALDH1A1
Cycloheptane SCHEMBL31385525 0.75
Pyrrole SCHEMBL10930986 0.75
Cyclohexane SCHEMBL28349733 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230248651-A1 METHODS FOR FABRICATING ISOLATED MICRO- OR NANO-STRUCTURES USING SOFT OR IMPRINT LITHOGRAPHY THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2023-08-10 US disclosed
US-11642313-B2 Methods for fabricating isolated micro- or nano-structures using soft or imprint lithography THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2023-05-09 US disclosed
US-20210059940-A1 METHODS FOR FABRICATING ISOLATED MICRO- OR NANO-STRUCTURES USING SOFT OR IMPRINT LITHOGRAPHY THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2021-03-04 US disclosed
US-10842748-B2 Methods for fabricating isolated micro- or nano-structures using soft or imprint lithography THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2020-11-24 US disclosed
US-20200078301-A1 METHODS FOR FABRICATING ISOLATED MICRO- OR NANO-STRUCTURES USING SOFT OR IMPRINT LITHOGRAPHY THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2020-03-12 US disclosed
CN-109836822-A A kind of soluble conductive polypyrrole and preparation method thereof that poly ion liquid is modified 东华大学 2019-06-04 CN disclosed
CN-109810250-A A kind of preparation method of soluble conductive polypyrrole 东华大学 2019-05-28 CN disclosed
EP-2534151-B1 8-METHYL-1-PHENYL-IMIDAZOL[1,5-A]PYRAZINE COMPOUNDS MERCK SHARP & DOHME (NL) 2018-11-14 EP disclosed
US-20180116959-A1 METHODS FOR FABRICATING ISOLATED MICRO- OR NANO-STRUCTURES USING SOFT OR IMPRINT LITHOGRAPHY NATIONAL SCIENCE FOUNDATION 2018-05-03 US disclosed
CN-107849023-A Bicyclic lactams and methods of use thereof 豪夫迈·罗氏有限公司 2018-03-27 CN disclosed
WO-1995030638-A1 PROCESS FOR PREPARING INTERMEDIATES FOR THE SYNTHESIS OF ANTIFUNGAL AGENTS SCHERING CORPORATION (US) 1995-11-16 WO disclosed
US-5442093-A Heating mixture of difluorobenzene derivative, allene, dialkyl malonate, base in polar organic solvent with catalyst in sealed vessel at specified pressure SCHERING CORPORATION (US) 1995-08-15 US disclosed
WO-1995016658-A1 PROCESS FOR PREPARING INTERMEDIATES FOR THE SYNTHESIS OF ANTIFUNGAL AGENTS SCHERING CORPORATION (US) 1995-06-22 WO disclosed
WO-1995016658-A1 PROCESS FOR PREPARING INTERMEDIATES FOR THE SYNTHESIS OF ANTIFUNGAL AGENTS SCHERING CORPORATION (US) 1995-06-22 WO disclosed
US-5403937-A Process for preparing intermediates for the synthesis of antifungal agents SCHERING CORPORATION (US) 1995-04-04 US disclosed
US-5403937-A Process for preparing intermediates for the synthesis of antifungal agents SCHERING CORPORATION (US) 1995-04-04 US disclosed
WO-1994025452-A1 PROCESS FOR PREPARING INTERMEDIATES FOR THE SYNTHESIS OF ANTIFUNGAL AGENTS SCHERING CORPORATION (US) 1994-11-10 WO disclosed
WO-1994025452-A1 PROCESS FOR PREPARING INTERMEDIATES FOR THE SYNTHESIS OF ANTIFUNGAL AGENTS SCHERING CORPORATION (US) 1994-11-10 WO disclosed
US-5349099-A Process for preparing intermediates for the synthesis of antifungal agents SCHERING CORPORATION (US) 1994-09-20 US disclosed
US-5349099-A Process for preparing intermediates for the synthesis of antifungal agents SCHERING CORPORATION (US) 1994-09-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11642313-B2 Methods for fabricating isolated micro- or nano-structures using soft or imprint lithography PFN1, FLNA, FSCN1 ALDH1A1 3501/4885
US-20210059940-A1 METHODS FOR FABRICATING ISOLATED MICRO- OR NANO-STRUCTURES USING SOFT OR IMPRINT LITHOGRAPHY PFN1, FLNA, FSCN1 ALDH1A1 3501/4885
US-10842748-B2 Methods for fabricating isolated micro- or nano-structures using soft or imprint lithography PFN1, FLNA, FSCN1 ALDH1A1 3501/4885
US-20200078301-A1 METHODS FOR FABRICATING ISOLATED MICRO- OR NANO-STRUCTURES USING SOFT OR IMPRINT LITHOGRAPHY PFN1, FLNA, FSCN1 ALDH1A1 3501/4885
US-20180116959-A1 METHODS FOR FABRICATING ISOLATED MICRO- OR NANO-STRUCTURES USING SOFT OR IMPRINT LITHOGRAPHY PFN1, FLNA, FSCN1 ALDH1A1 3501/4885
US-20230248651-A1 METHODS FOR FABRICATING ISOLATED MICRO- OR NANO-STRUCTURES USING SOFT OR IMPRINT LITHOGRAPHY PFN1, FLNA, FSCN1 ALDH1A1 3501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.