Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.49 |
| ▸ | ABAT | P80404 | 1/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6435776 | 0.88 | ALDH5A1 (0.53) | ALDH5A1ABATVCAM1ALDH1A1MAPT | |
| SCHEMBL16950538 | 0.86 | APP (0.40) | ALDH5A1ABATVCAM1ALDH1A1MAPT | |
| SCHEMBL16952667 | 0.86 | APP (0.43) | ALDH5A1ABATALDH1A1MAPTHPGD | |
| SCHEMBL7626416 | 0.81 | ALDH5A1 (0.47) | ALDH5A1ABATVCAM1ALDH1A1MAPT | |
| SCHEMBL30135443 | 0.79 | TDP1 (0.55) | ALDH1A1MAPTHTTSMN1; SMN2MEN1 | |
| SCHEMBL1159451 | 0.79 | ALDH1A1 (0.64) | ALDH5A1ABATVCAM1ALDH1A1MAPT | |
| SCHEMBL30268627 | 0.79 | ALDH1A1 (0.64) | ALDH5A1ABATVCAM1ALDH1A1MAPT | |
| SCHEMBL973890 | 0.79 | TDP1 (0.55) | ALDH1A1MAPTHTTSMN1; SMN2MEN1 | |
| SCHEMBL2207272 | 0.78 | TDP1 (0.53) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL16956608 | 0.78 | TSHR (0.55) | ALDH1A1MAPTLMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106170486-A | Novel indazolecarboxamides, method for the production thereof, pharmaceutical preparations containing the same and use thereof for producing medicaments | 拜耳医药股份有限公司 | 2016-11-30 | — | — | CN | disclosed |