Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | XPO1 | O14980 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | JUN | P05412 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12615369 | 0.81 | SLC6A3 (0.38) | POLBMAPTALDH1A1SMN1; SMN2JUN | |
| SCHEMBL3822431 | 0.81 | POLB (0.37) | DHODHKMT2AHPGDPOLBKEAP1 | |
| SCHEMBL1015670 | 0.79 | HSD11B1 (0.50) | DHODHKMT2AHPGDPOLBKEAP1 | |
| SCHEMBL19627329 | 0.77 | CSNK1D (0.45) | DHODHKMT2AMEN1HPGDPOLB | |
| SCHEMBL1014340 | 0.77 | KDM4E (0.40) | DHODHKMT2APOLBKEAP1NFE2L2 | |
| SCHEMBL1016549 | 0.76 | KMT2A (0.37) | DHODHKMT2AMEN1HPGDPOLB | |
| SCHEMBL1014948 | 0.76 | MEN1 (0.46) | DHODHKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL8140882 | 0.76 | KDM4E (0.39) | DHODHKMT2AHPGDPOLBKEAP1 | |
| SCHEMBL1759984 | 0.76 | PDE4B (0.40) | DHODHKMT2APOLBKEAP1NFE2L2 | |
| SCHEMBL28073266 | 0.76 | CSNK2A1 (0.39) | DHODHSMN1; SMN2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104203950-B | Liver x receptor modulators | 生命医药公司 | 2016-08-24 | — | — | CN | disclosed |