SCHEMBL28087992

SCHEMBL28087992

COC(=O)c1cccc(C(=O)OI)c1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.50
TSHR P16473 1/20 0.50
ALDH1A1 P00352 4/20 0.48
CFTR P13569 1/20 0.48
HSD17B10 Q99714 1/20 0.48
FFAR4 Q5NUL3 1/20 0.48
POLB P06746 2/20 0.47
KDM4E B2RXH2 2/20 0.47
ATM Q13315 1/20 0.47
MYC P01106 1/20 0.46
RAB9A P51151 1/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA9 Q16790 2/20 0.44
CA12 O43570 1/20 0.44
CA7 P43166 1/20 0.44
CA14 Q9ULX7 1/20 0.44
CA5A P35218 1/20 0.43
MAPT P10636 1/20 0.43
ALOX15 P16050 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3511612 0.90 LMNA (0.59) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL21162614 0.86 TSHR (0.61) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL164597 0.82 TSHR (0.53) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL27933732 0.82 MEN1 (0.48) LMNATSHRALDH1A1HSD17B10POLB
SCHEMBL16953017 0.82 LMNA (0.52) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL29753082 0.81 LMNA (0.50) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL1585766 0.81 LMNA (0.50) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL28703029 0.81 LMNA (0.50) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL29934048 0.81 ALDH1A1 (0.53) LMNATSHRALDH1A1CFTRHSD17B10
SCHEMBL19726720 0.81 LMNA (0.50) LMNATSHRALDH1A1CFTRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104549164-B Micropore metal organic framework materials adsorbed for methane and acetylene and store and preparation method thereof 浙江大学 2016-08-24 CN claimed
CN-104549164-B Micropore metal organic framework materials adsorbed for methane and acetylene and store and preparation method thereof 浙江大学 2016-08-24 CN disclosed