SCHEMBL28088464

SCHEMBL28088464

CCCCCCCCC(CCCCCCCC)c1cc2ccccc2[nH]1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 1/20 0.45
MAPT P10636 1/20 0.45
DRD2 P14416 2/20 0.43
DRD3 P35462 1/20 0.43
EZH2 Q15910 1/20 0.43
ALOX5 P09917 1/20 0.41
GAA P10253 1/20 0.40
HPGD P15428 1/20 0.40
CTSV O60911 1/20 0.39
CTSL P07711 1/20 0.39
CCKBR P32239 1/20 0.39
LOXL2 Q9Y4K0 1/20 0.39
AOC3 Q16853 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10774538 1.00 KDM4E (0.45) KDM4EALDH1A1MAPTDRD2DRD3
SCHEMBL28890610 1.00 KDM4E (0.45) KDM4EALDH1A1MAPTDRD2DRD3
SCHEMBL9225107 0.97 DRD2 (0.44) KDM4EALDH1A1MAPTDRD2DRD3
SCHEMBL9227391 0.95 KDM4E (0.42) KDM4EALDH1A1MAPTDRD2DRD3
SCHEMBL2356508 0.93 LOXL2 (0.41) KDM4EALDH1A1MAPTDRD2DRD3
SCHEMBL22931310 0.88 DRD2 (0.49) KDM4EALDH1A1MAPTDRD2DRD3
SCHEMBL30863902 0.88 DRD2 (0.45) KDM4EALDH1A1MAPTDRD2DRD3
SCHEMBL29933737 0.86 DRD2 (0.41) KDM4EALDH1A1MAPTDRD2DRD3
SCHEMBL9169029 0.86 DAGLA (0.41) KDM4EALDH1A1MAPTDRD2DRD3
SCHEMBL11168360 0.86 ALOX5 (0.43) KDM4EALDH1A1MAPTDRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108707221-B Conjugated polymer based on naphthoindene fluorene high two-photon absorption and preparation method and application thereof 华南理工大学 2021-02-19 CN disclosed
CN-107759775-B Donor-receptor type alternating polymer containing sulfone-based fused ring structure and having strong two-photon effect, preparation method and application 华南协同创新研究院 2020-06-05 CN disclosed
CN-106243329-B One kind being based on S, and S- dioxydibenze thiophthene derivative replaces conjugated polymer luminescent material and the preparation method and application thereof to receptor type 华南理工大学 2019-06-18 CN disclosed
CN-107540823-A One kind is based on S, the strong two-photon absorption conjugated polymer of S dioxydibenze bithiophene units and preparation method and application 华南理工大学 2018-01-05 CN disclosed
CN-106243329-A One is based on S, S dioxydibenze thiophthene derivative replaces conjugated polymer luminescent material and preparation method and application to receptor type 华南理工大学 2016-12-21 CN disclosed
CN-104004165-B Electron donor polymer and application thereof containing S, S-dioxo-dibenzothiophene unit 华南理工大学 2016-08-24 CN disclosed