SCHEMBL8975153

SCHEMBL8975153

CCCCCNC(CC)CO

nearest known ligand 0.70

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.70
KDM4E B2RXH2 2/20 0.70
CNR1 P21554 2/20 0.70
ADRA1A P35348 1/20 0.70
TDP1 Q9NUW8 1/20 0.70
SMN1; SMN2 Q16637 2/20 0.67
ABCC3 O15438 1/20 0.67
ALDH1A1 P00352 5/20 0.42
TSHR P16473 1/20 0.40
EPHX1 P07099 5/20 0.37
NAAA Q02083 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9620151 0.98 LMNA (0.67) LMNAKDM4ECNR1ADRA1ATDP1
SCHEMBL16628357 0.98 LMNA (0.67) LMNAKDM4ECNR1ADRA1ATDP1
SCHEMBL6249617 0.98 LMNA (0.67) LMNAKDM4ECNR1ADRA1ATDP1
SCHEMBL4781590 0.93 LMNA (0.73) LMNAKDM4ECNR1ADRA1ATDP1
SCHEMBL1219703 0.91 LMNA (0.54) LMNAKDM4ECNR1ADRA1ATDP1
SCHEMBL1223599 0.88 LMNA (0.52) LMNAKDM4ECNR1ADRA1ATDP1
SCHEMBL2346969 0.88 LMNA (0.52) LMNAKDM4ECNR1ADRA1ATDP1
Methyl Alcohol SCHEMBL28137239 0.88 LMNA (0.52) LMNAKDM4ECNR1ADRA1ATDP1
SCHEMBL1222755 0.88 LMNA (0.52) LMNAKDM4ECNR1ADRA1ATDP1
SCHEMBL1222862 0.88 LMNA (0.52) LMNAKDM4ECNR1ADRA1ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-58198296-A None JP disclosed
JP-59039294-A None JP disclosed
EP-2860170-B1 PROCESS FOR PREPARING 4-HYDROXYBUTYL ACRYLATE OSAKA ORGANIC CHEMICAL IND LTD (JP) 2019-08-28 EP disclosed
CN-104220413-B Method for producing 4-hydroxybutyl acrylate 大阪有机化学工业株式会社 2018-12-04 CN disclosed
EP-3015449-B1 (METH)ACRYLATE PRODUCTION SYSTEM OSAKA ORGANIC CHEMICAL IND LTD (JP) 2018-10-10 EP disclosed
US-9670129-B2 Process for preparing 4-hydroxybutyl acrylate OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) 2017-06-06 US disclosed
US-20160136538-A1 (METH)ACRYLATE PRODUCTION SYSTEM OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) 2016-05-19 US disclosed
EP-3015449-A1 (METH)ACRYLATE PRODUCTION SYSTEM Osaka Organic Chemical Ind., Ltd. (JP) 2016-05-04 EP disclosed
US-20150126766-A1 PROCESS FOR PREPARING 4-HYDROXYBUTYL ACRYLATE OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) 2015-05-07 US disclosed
EP-2860170-A1 PROCESS FOR PREPARING 4-HYDROXYBUTYL ACRYLATE Osaka Organic Chemical Ind., Ltd. (JP) 2015-04-15 EP disclosed
EP-0404146-B1 Enantiomeric enrichment and stereoselective synthesis of chiral amines CELGENE CORP (US) 1996-03-20 EP disclosed
US-5300437-A Using omega-amino acid transaminase CELGENE CORPORATION (US) 1994-04-05 US disclosed
EP-0343477-B1 Dispersion polymers based on ethylenically unsaturated monomers containing urea groups, process for their preparation and their use HOECHST AG (DE) 1993-12-01 EP disclosed
US-5169780-A Conversion to ketone in aqueous solution with amino acceptor and omega-amino acid acceptor; solvent extraction CELGENE CORPORATION (US) 1992-12-08 US disclosed
EP-0404146-A2 Enantiomeric enrichment and stereoselective synthesis of chiral amines CELGENE CORPORATION (US) 1990-12-27 EP disclosed
US-4950606-A CONTACTING IN AN AQUEOUS MEDIUM IN THE PRESENCE OF AN AMINO ACCEPTOR WITH AN OMEGA-AMINO ACID TRANSAMINASE TO CONVERT ONE OF AMINES TO KETONE CELGENE CORPORATION (US) 1990-08-21 US disclosed
EP-0343477-A2 Dispersion polymers based on ethylenically unsaturated monomers containing urea groups, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1989-11-29 EP disclosed
EP-0315876-A2 Dispersion copolymers containing urethane groups, based on olefinically unsaturated monomers, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-17 EP disclosed
JP-S5939294-A PREPARATION OF OPTICAL ACTIVE 2-AMINO-1-BUTANOL HAMARI YAKUHIN KOGYO KK 1984-03-03 JP disclosed
JP-S58198296-A PRODUCTION OF D-2-AMINOBUTANOL CHISSO CORP 1983-11-18 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150126766-A1 PROCESS FOR PREPARING 4-HYDROXYBUTYL ACRYLATE LTB4R2, LTA4H, LTB4R LMNA 1413/4885KDM4E 3193/4885CNR1 3836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.