SCHEMBL28089133

SCHEMBL28089133

O=COCc1ccc(C2CC2)c(Cl)n1.[Ar]

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CEL P19835 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28088983 0.98 CEL (0.32) CEL
SCHEMBL28089127 0.82
SCHEMBL28835361 0.81 CNR2 (0.33)
SCHEMBL28089139 0.74 CNR2 (0.51)
SCHEMBL28089125 0.74 CNR2 (0.45)
SCHEMBL28089149 0.72 SRC (0.32)
SCHEMBL28659624 0.70 KCNH2 (0.40)
SCHEMBL28119095 0.70 CYP3A4 (0.38)
SCHEMBL28282890 0.69 XPO1 (0.43)
SCHEMBL28089009 0.69 MBOAT4 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103608332-B Pyridine-2-amides useful as CB2 agonists 霍夫曼-拉罗奇有限公司 2016-09-28 CN disclosed