Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 11/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29388965 | 0.84 | RPS6KA5 (0.45) | NFE2L2RPS6KA5HSD11B1TRPV1LMNA | |
| SCHEMBL120643 | 0.84 | RPS6KA5 (0.45) | NFE2L2RPS6KA5HSD11B1TRPV1LMNA | |
| Hydrochloric Acid SCHEMBL30667166 | 0.82 | RPS6KA5 (0.44) | NFE2L2RPS6KA5HSD11B1TRPV1LMNA | |
| Formic Acid Methyl Ester SCHEMBL25291105 | 0.78 | NFE2L2 (0.41) | NFE2L2LMNASMN1; SMN2 | |
| Formic Acid Methyl Ester SCHEMBL27958586 | 0.75 | NFE2L2 (0.49) | NFE2L2LMNA | |
| SCHEMBL4679589 | 0.73 | LMNA (0.38) | NFE2L2SLC22A12RPS6KA5HSD11B1CNR2 | |
| SCHEMBL586118 | 0.72 | NFE2L2 (0.48) | NFE2L2HSD11B1TRPV1LMNA | |
| SCHEMBL2092601 | 0.71 | NFE2L2 (0.50) | NFE2L2SLC22A12HSD11B1LMNA | |
| SCHEMBL14480040 | 0.71 | NFE2L2 (0.44) | NFE2L2SLC22A12 | |
| SCHEMBL11400822 | 0.71 | SMN1; SMN2 (0.39) | NFE2L2RPS6KA5HSD11B1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106349156-A | Pyridine-2-amides capable of being used as CB2 agonist | 霍夫曼-拉罗奇有限公司 | 2017-01-25 | — | — | CN | disclosed |
| CN-103608332-B | Pyridine-2-amides useful as CB2 agonists | 霍夫曼-拉罗奇有限公司 | 2016-09-28 | — | — | CN | disclosed |