Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.64 |
| ▸ | CA1 | P00915 | 4/20 | 0.64 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.41 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28262170 | 0.98 | CA2 (0.62) | CA2CA1GABRR1ZDHHC7CPB2 | |
| SCHEMBL9597159 | 0.88 | CA2 (0.71) | CA2CA1ZDHHC7CPB2BIRC2 | |
| SCHEMBL21052458 | 0.86 | CA2 (0.75) | CA2CA1ZDHHC7USP2TSHR | |
| SCHEMBL15442726 | 0.84 | CA2 (0.67) | CA2CA1ZDHHC7USP2TSHR | |
| Hydrochloric Acid SCHEMBL4411000 | 0.83 | CA2 (0.65) | CA2CA1ZDHHC7CPB2MAPK1 | |
| Hydrochloric Acid SCHEMBL4334151 | 0.83 | CA2 (0.65) | CA2CA1ZDHHC7CPB2MAPK1 | |
| SCHEMBL15592501 | 0.83 | CPB2 (0.53) | CA2CA1GABRR1CPB2KMT2A | |
| SCHEMBL3989203 | 0.82 | — | — | |
| SCHEMBL3989206 | 0.82 | — | — | |
| SCHEMBL17617129 | 0.82 | CA2 (0.76) | CA2CA1ZDHHC7USP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106349156-A | Pyridine-2-amides capable of being used as CB2 agonist | 霍夫曼-拉罗奇有限公司 | 2017-01-25 | — | — | CN | disclosed |
| CN-103608332-B | Pyridine-2-amides useful as CB2 agonists | 霍夫曼-拉罗奇有限公司 | 2016-09-28 | — | — | CN | disclosed |