Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 11/20 | 0.32 |
| ▸ | CCL2 | P13500 | 9/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28089151 | 0.89 | KDM4E (0.36) | KDM4EALDH1A1BRD4CCL2 | |
| SCHEMBL28089132 | 0.83 | BRD4 (0.33) | BRD4CCL2 | |
| SCHEMBL28043653 | 0.81 | BRD4 (0.35) | BRD4CCL2 | |
| SCHEMBL28507942 | 0.81 | BRD4 (0.32) | ALDH1A1BRD4CCL2SRD5A1 | |
| SCHEMBL28089129 | 0.78 | BRD4 (0.49) | KDM4EALDH1A1BRD4CCL2 | |
| Hydrochloric Acid SCHEMBL27913881 | 0.77 | BRD4 (0.47) | KDM4EALDH1A1BRD4CCL2 | |
| SCHEMBL28001004 | 0.75 | CHEK1 (0.33) | BRD4CCL2 | |
| SCHEMBL28089257 | 0.73 | ERN1 (0.39) | BRD4 | |
| SCHEMBL28089286 | 0.72 | ADORA3 (0.33) | BRD4CCL2 | |
| SCHEMBL27707872 | 0.66 | CHRNB2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105828820-A | Bromodomain inhibitors | 赛尔基因昆蒂赛尔研究公司 | 2016-08-03 | — | — | CN | disclosed |