Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | RBM17 | Q96I25 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29644544 | 0.93 | ENPP2 (0.52) | ENPP2TRPV4MEN1KMT2ASLC6A2 | |
| SCHEMBL385535 | 0.93 | ENPP2 (0.52) | ENPP2TRPV4MEN1KMT2ASLC6A2 | |
| SCHEMBL594878 | 0.82 | POLB (0.38) | POLBTRPV4MEN1KMT2ASLC6A2 | |
| SCHEMBL19204646 | 0.81 | TRPV4 (0.44) | ENPP2POLBTRPV4MEN1KMT2A | |
| SCHEMBL594879 | 0.80 | TTR (0.37) | POLBTRPV4MEN1KMT2ASLC6A2 | |
| SCHEMBL20704942 | 0.77 | ENPP2 (0.44) | ENPP2TRPV4MEN1KMT2ASLC6A2 | |
| SCHEMBL29447064 | 0.77 | ENPP2 (0.44) | ENPP2TRPV4MEN1KMT2ASLC6A2 | |
| SCHEMBL322537 | 0.77 | ENPP2 (0.52) | ENPP2POLBTRPV4MEN1KMT2A | |
| SCHEMBL29952519 | 0.76 | TSHR (0.49) | ENPP2MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL1686371 | 0.76 | TSHR (0.49) | ENPP2MEN1KMT2ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008571-A | Boron-containing small molecules | 安纳考尔医药公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-106008583-A | BORON-CONTAINING SMALL MOLECULES | 安纳考尔医药公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-105949230-A | BORON-CONTAINING SMALL MOLECULES | 安纳考尔医药公司 | 2016-09-21 | — | — | CN | disclosed |