SCHEMBL385535

SCHEMBL385535

COc1cc(Cl)ccc1B(O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 2/20 0.52
TRPV4 Q9HBA0 1/20 0.47
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
ERN1 O75460 1/20 0.42
EGFR P00533 1/20 0.42
TTR P02766 2/20 0.41
TUBB4A P04350 4/20 0.41
TUBB P07437 4/20 0.41
TUBA3C P0DPH7 4/20 0.41
TUBA1B P68363 4/20 0.41
TUBA4A P68366 4/20 0.41
TUBB4B P68371 4/20 0.41
TUBB3 Q13509 4/20 0.41
TUBB2A Q13885 4/20 0.41
TUBB8 Q3ZCM7 4/20 0.41
TUBA3E Q6PEY2 4/20 0.41
TUBA1A Q71U36 4/20 0.41
TUBA1C Q9BQE3 4/20 0.41
TUBB6 Q9BUF5 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29644544 1.00 ENPP2 (0.52) ENPP2TRPV4MEN1KMT2AERN1
Ethylene Glycol SCHEMBL28089477 0.93 ENPP2 (0.46) ENPP2TRPV4MEN1KMT2AERN1
SCHEMBL19204646 0.88 TRPV4 (0.44) ENPP2TRPV4MEN1KMT2AERN1
SCHEMBL322537 0.83 ENPP2 (0.52) ENPP2TRPV4MEN1KMT2AERN1
SCHEMBL25308686 0.80 ENPP2 (0.41) ENPP2TTRSLC6A2SLC6A4SLC6A3
SCHEMBL20704942 0.80 ENPP2 (0.44) ENPP2TRPV4MEN1KMT2ASLC6A2
SCHEMBL29447064 0.80 ENPP2 (0.44) ENPP2TRPV4MEN1KMT2ASLC6A2
SCHEMBL29952519 0.79 TSHR (0.49) ENPP2MEN1KMT2ASLC6A2SLC6A4
SCHEMBL1686371 0.79 TSHR (0.49) ENPP2MEN1KMT2ASLC6A2SLC6A4
SCHEMBL15330282 0.78 PLAU (0.44) ENPP2LMNAFLT1KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 488 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114763340-A Organic compound, application and preparation method thereof, and organic electroluminescent device using organic compound 北京鼎材科技有限公司 2022-07-19 CN claimed
US-20260150574-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DIODE, ORGANIC OPTOELECTRONIC DIODE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2026-05-28 US disclosed
US-12583843-B2 Organic light-emitting device, method for manufacturing same, and composition for organic material layer of organic light-emitting device LT MATERIALS CO., LTD. (KR) 2026-03-24 US disclosed
US-12534464-B2 Heterocyclic compound and organic light emitting element comprising same LT MATERIALS CO., LTD. (KR) 2026-01-27 US disclosed
US-12507589-B2 Organic light emitting device LG CHEM, LTD. (KR) 2025-12-23 US disclosed
US-12492191-B2 Organic light emitting device LG CHEM, LTD. (KR) 2025-12-09 US disclosed
US-20250340563-A1 FUSED PYRIDAZINE DERIVATIVES AS NLRP3 INHIBITORS TAKEDA DEVELOPMENT CENTER AMERICAS, INC. 2025-11-06 US disclosed
US-20250333383-A1 N-OXIDE COMPOUNDS AND USE THEREOF SK BIOPHARMACEUTICALS CO., LTD. (KR) 2025-10-30 US disclosed
US-12453283-B2 Compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2025-10-21 US disclosed
US-12402529-B2 Organic compound, composition, organic optoelectronic device, and display device SAMSUNG SDI CO., LTD. (KR) 2025-08-26 US disclosed
US-7345058-B2 (1-Methyl-5-phenyl-1H-pyrazol-4-yl)-(trans-octahydro-isoquinolin-2-yl)methanone; 11 beta -hydroxysteroid dehydrogenase inhibitor; upregulation of phosphoenolpyruvate carboxykinase (PEPCK) and glucose-6-phosphatase (G6Pase); antidiabetic agent; type II diabetes mellitus and metabolic syndrome HOFFMANN-LA ROCHE INC. (US) 2008-03-18 US disclosed
WO-2007134862-A1 SUBSTITUTED ARYLIMIDAZ0L0NE AND TRIAZ0L0NE AS INHIBITORS OF VASOPRESSIN RECEPTORS BAYER HEALTHCARE AG (DE) 2007-11-29 WO disclosed
US-20070167622-A1 [2-(3-chloro-phenyl)-thiazol-4-yl]-(octahydro-quinolin-1-yl)-methanone; azocan-1-yl-[2-(2,3-dichloro-phenyl)-thiazol-4-yl]-methanone; type II diabetes mellitus and metabolic syndrome GILLESPIE PAUL 2007-07-19 US disclosed
WO-2007039467-A1 PYRIMIDINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS CELLZOME (UK) LTD. (GB) 2007-04-12 WO disclosed
US-20060223852-A1 Pyrazoles GILLESPIE PAUL 2006-10-05 US disclosed
EP-1638578-A2 HYDROLYTICALLY-RESISTANT BORON-CONTAINING THERAPEUTICS AND METHODS OF USE Anacor Pharmaceuticals, Inc. (US) 2006-03-29 EP disclosed
WO-2005013892-A9 HYDROLYTICALLY-RESISTANT BORON-CONTAINING THERAPEUTICS AND METHODS OF USE ANACOR PHARMACEUTICALS INC (US) 2005-04-14 WO disclosed
US-20050054644-A1 Hydrolytically-resistant boron-containing therapeutics and methods of use ANACOR PHARMACEUTICALS, LLC 2005-03-10 US disclosed
WO-2005013892-A2 HYDROLYTICALLY-RESISTANT BORON-CONTAINING THERAPEUTICS AND METHODS OF USE ANACOR PHARMACEUTICALS, INC. (US) 2005-02-17 WO disclosed
US-20030229067-A1 Pyrrolopyrimidine A2b selective antagonist compounds, their synthesis and use OSI PHARMACEUTICALS, INC. 2003-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030229067-A1 Pyrrolopyrimidine A2b selective antagonist compounds, their synthesis and use ADORA2B, OXER1, CNR1 ENPP2 2202/4885TRPV4 812/4885MEN1 4584/4885
US-20250333383-A1 N-OXIDE COMPOUNDS AND USE THEREOF SCNN1B, SCN1B, SCN2B ENPP2 1629/4885TRPV4 119/4885MEN1 1568/4885
US-20060223852-A1 Pyrazoles GPR119, PDK2, PC ENPP2 2749/4885TRPV4 3513/4885MEN1 1522/4885
US-12453283-B2 Compound and organic light emitting device comprising the same CRY1, CYP1A1, CHRM1 ENPP2 2171/4885TRPV4 1178/4885MEN1 788/4885
US-12534464-B2 Heterocyclic compound and organic light emitting element comprising same NR2E3, CDYL, CRY2 ENPP2 4444/4885TRPV4 3136/4885MEN1 1912/4885
US-20250340563-A1 FUSED PYRIDAZINE DERIVATIVES AS NLRP3 INHIBITORS NLRP3, NLRP1, NOD1 ENPP2 2293/4885TRPV4 2224/4885MEN1 3679/4885
US-12583843-B2 Organic light-emitting device, method for manufacturing same, and composition for organic material layer of organic light-emitting device OXER1, RPL22, POR ENPP2 2057/4885TRPV4 2245/4885MEN1 2123/4885
US-20070167622-A1 [2-(3-chloro-phenyl)-thiazol-4-yl]-(octahydro-quinolin-1-yl)-methanone; azocan-1-yl-[2-(2,3-dichloro-phenyl)-thiazol-4-yl]-methanone; type II diabetes mellitus and metabolic syndrome GOT2, PC, CYP11B2 ENPP2 4168/4885TRPV4 2551/4885MEN1 702/4885
US-12402529-B2 Organic compound, composition, organic optoelectronic device, and display device OCIAD1, OXER1, OR10J3 ENPP2 3258/4885TRPV4 80/4885MEN1 1263/4885
US-20050054644-A1 Hydrolytically-resistant boron-containing therapeutics and methods of use BTD, GAA, GBA3 ENPP2 646/4885TRPV4 4716/4885MEN1 1241/4885
US-12492191-B2 Organic light emitting device CYP1A1, ARNT, AOC3 ENPP2 2984/4885TRPV4 1347/4885MEN1 2411/4885
US-20260150574-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DIODE, ORGANIC OPTOELECTRONIC DIODE, AND DISPLAY DEVICE OXER1, OR10J3, OPRD1 ENPP2 3782/4885TRPV4 859/4885MEN1 2349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.