Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL5534765 | 0.94 | RAB9A (0.32) | CA1CA2CA9RAB9AKDM4E | |
| Urea SCHEMBL5851743 | 0.83 | ALDH1A1 (0.40) | — | |
| Acetone SCHEMBL15260481 | 0.83 | LMNA (0.40) | RAB9A | |
| Benzene SCHEMBL27559301 | 0.81 | GALR1 (0.30) | — | |
| Methyl Alcohol SCHEMBL27394697 | 0.81 | — | — | |
| SCHEMBL25309793 | 0.81 | — | — | |
| SCHEMBL9623601 | 0.81 | — | — | |
| SCHEMBL5697098 | 0.81 | — | — | |
| SCHEMBL9623851 | 0.81 | — | — | |
| SCHEMBL9623859 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105771601-A | Self-Concentrating Absorbent for Acid Gas Separation | 胡亮 | 2016-07-20 | — | — | CN | claimed |
| CN-111630702-A | Nonaqueous electrolyte for battery and lithium secondary battery | 三井化学株式会社 | 2020-09-04 | — | — | CN | disclosed |
| CN-110408062-A | Optical film | SUMITOMO CHEMICAL CORP | 2019-11-05 | — | — | CN | disclosed |
| CN-110234687-A | Polyimides mesentery and laminated body | 住友化学株式会社 | 2019-09-13 | — | — | CN | disclosed |
| CN-107112139-B | Method for manufacturing electrolytic capacitor | 松下知识产权经营株式会社 | 2019-07-26 | — | — | CN | disclosed |
| CN-109765642-A | Optical laminate | 住友化学株式会社 | 2019-05-17 | — | — | CN | disclosed |
| CN-107112139-A | Method for manufacturing electrolytic capacitor | 松下知识产权经营株式会社 | 2017-08-29 | — | — | CN | disclosed |
| CN-107004508-A | Electrolytic capacitor and its manufacture method | 松下知识产权经营株式会社 | 2017-08-01 | — | — | CN | disclosed |