Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 9/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 9/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28089580 | 1.00 | TSHR (0.40) | TSHRHCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL28089452 | 0.84 | VCAM1 (0.53) | VCAM1 | |
| SCHEMBL14905820 | 0.76 | CASP3 (0.59) | TSHRHCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL28089587 | 0.76 | FKBP1A (0.56) | MEN1KMT2AHTT | |
| SCHEMBL14895020 | 0.72 | TSHR (0.58) | TSHRHCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL14895449 | 0.72 | TSHR (0.58) | TSHRHCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL14895021 | 0.72 | TSHR (0.58) | TSHRHCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL28926487 | 0.70 | TAAR1 (0.44) | TSHRMEN1KMT2APLAU | |
| SCHEMBL28926520 | 0.70 | TAAR1 (0.44) | TSHRMEN1KMT2APLAU | |
| SCHEMBL16169932 | 0.69 | PSEN1 (0.60) | TSHRHCRTR1HCRTR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103958505-B | For treating dibasic 3,4-diaminourea-3-cyclobutane-1,2-dione compounds of chemokine mediated pathology | 高德美研究及发展公司 | 2016-08-24 | — | — | CN | disclosed |