Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | CASP1 | P29466 | 1/20 | 0.62 |
| ▸ | CASP7 | P55210 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL29138109 | 1.00 | CYP3A4 (0.62) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| Sulfuric Acid SCHEMBL9681860 | 0.87 | CYP3A4 (0.48) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| Propane SCHEMBL27468712 | 0.87 | CYP3A4 (0.71) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| Questiomycin B SCHEMBL27305569 | 0.84 | ALOX15 (0.75) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| O-Tolylamine SCHEMBL8972194 | 0.84 | CYP3A4 (0.71) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| Methyl Alcohol SCHEMBL9725170 | 0.83 | CYP3A4 (0.77) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| Alcohol SCHEMBL11612801 | 0.82 | TSHR (0.71) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| Methyl Alcohol SCHEMBL27963626 | 0.80 | CYP3A4 (0.71) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| Alcohol SCHEMBL11877367 | 0.80 | ALDH1A1 (0.82) | CYP3A4SMN1; SMN2ALDH1A1CYP1A2CYP2C9 | |
| Hydrogen Peroxide SCHEMBL5481727 | 0.79 | CYP3A4 (0.83) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117825301-A | Detection reagent package and detection method for inorganic selenium in water sample | 江西中医药大学 | 2024-04-05 | — | — | CN | claimed |
| CN-113105511-A | Method for generating hydroxyl free radicals by using Schiff base cobalt complex | 南开大学 | 2021-07-13 | — | — | CN | claimed |
| CN-111205703-B | Crack visualized waterproof coating and preparation method thereof | 西南大学 | 2021-04-09 | — | — | CN | claimed |
| CN-108519365-B | Surface enhanced Raman spectroscopy sensor based on electrochemical deposition and molecular imprinting and preparation method thereof | 上海应用技术大学 | 2021-02-26 | — | — | CN | claimed |
| CN-111205703-A | Crack visualized waterproof coating and preparation method thereof | 西南大学 | 2020-05-29 | — | — | CN | claimed |
| CN-110093158-A | A kind of fluorescent carbon quantum dot of N doping and its preparation method and application | 西北大学 | 2019-08-06 | — | — | CN | claimed |
| CN-106587005-B | A kind of step carbonation high-quantum efficiency carbon quantum dot and preparation method thereof | 上海纳米技术及应用国家工程研究中心有限公司 | 2018-11-16 | — | — | CN | claimed |
| CN-108519365-A | Surface enhanced Raman spectroscopy sensor and preparation method thereof based on electrochemical deposition and molecular engram | 上海应用技术大学 | 2018-09-11 | — | — | CN | claimed |
| CN-107760300-A | A kind of preparation method of rare earth compounding kaolin hybrid material | 龙岩学院 | 2018-03-06 | — | — | CN | claimed |
| CN-106008929-B | One kind closes Cd (II) oligometric comples dye sensitizing agent and preparation method thereof containing O-phenylene diamine derivatives | 湘潭大学 | 2018-01-23 | — | — | CN | claimed |
| CN-106587005-A | Multi-step carbonized high quantum efficiency carbon quantum dot and preparation method thereof | 上海纳米技术及应用国家工程研究中心有限公司 | 2017-04-26 | — | — | CN | claimed |
| CN-106008929-A | Dye sensitizer containing o-phenylenediamine derivative and Cd(II) polymeric complex and preparation method thereof | 湘潭大学 | 2016-10-12 | — | — | CN | claimed |
| CN-105295909-A | Method for using phenylenediamine and citric acid for preparing carbon quantum dot marking probe for cell developing | SH NAT ENG RES CT NANOTECH CO | 2016-02-03 | — | — | CN | claimed |
| CN-117825301-A | Detection reagent package and detection method for inorganic selenium in water sample | 江西中医药大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-117825301-A | Detection reagent package and detection method for inorganic selenium in water sample | 江西中医药大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-116344761-A | Porous carbon coated ternary positive electrode material and preparation method and application thereof | 蜂巢能源科技股份有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-106243328-A | A kind of thienyl-containing phenylenediamine derivative polymer-metal complex closing Zn (II) and preparation method thereof and purposes | 湘潭大学 | 2016-12-21 | — | — | CN | disclosed |
| CN-106008929-A | Dye sensitizer containing o-phenylenediamine derivative and Cd(II) polymeric complex and preparation method thereof | 湘潭大学 | 2016-10-12 | — | — | CN | disclosed |
| CN-103065751-B | A kind of preparation method based on the magnetic MFe2O4/C/M ' that phenyl amines organic molecule is carbon source | 中国科学院宁波材料技术与工程研究所 | 2016-08-10 | — | — | CN | disclosed |
| CN-105295909-A | Method for using phenylenediamine and citric acid for preparing carbon quantum dot marking probe for cell developing | SH NAT ENG RES CT NANOTECH CO | 2016-02-03 | — | — | CN | disclosed |