Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL29647896 | 0.87 | ALOX15 (0.62) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| Sulfuric Acid SCHEMBL147075 | 0.87 | ALOX15 (0.62) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| Alcohol SCHEMBL28089608 | 0.87 | CYP3A4 (0.62) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| Alcohol SCHEMBL29138109 | 0.87 | CYP3A4 (0.62) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| Sulfuric Acid SCHEMBL29559847 | 0.85 | ALOX15 (0.59) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| Sulfuric Acid SCHEMBL1599591 | 0.85 | ALOX15 (0.59) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| Sulfuric Acid SCHEMBL9293766 | 0.84 | GABRA1 (0.44) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL5564022 | 0.82 | CYP3A4 (0.56) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| Sulfuric Acid SCHEMBL9452067 | 0.82 | ALOX15 (0.56) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| Naphthalene SCHEMBL28031965 | 0.80 | PSIP1 (0.42) | CYP3A4SMN1; SMN2ALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108589332-A | A kind of work clothes antibacterial textile dyestuff and preparation method thereof | 徐州迈斯特机械科技有限公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-107435250-A | A kind of textile dyestuff of high stability | 肖彦彦 | 2017-12-05 | — | — | CN | disclosed |
| CN-107142748-A | Fade-proof textile dyestuff of a kind of antibacterial and preparation method thereof | 吴江市意胜纺织有限公司 | 2017-09-08 | — | — | CN | disclosed |
| CN-107142748-A | Fade-proof textile dyestuff of a kind of antibacterial and preparation method thereof | 吴江市意胜纺织有限公司 | 2017-09-08 | — | — | CN | disclosed |
| US-5167669-A | Hair dyes | L'OREAL (FR) | 1992-12-01 | — | — | US | disclosed |
| US-5096455-A | PROCESS FOR DYEING KERATINOUS FIBRES EMPLOYING AN INDOLE DYE AND AT LEAST ONE PARA-PHENYLENEDIAMINE CONTAINING A SECONDARY AMINO GROUP ABSENT AN OXIDANT OTHER THAN AIR | L'OREAL (FR) | 1992-03-17 | — | — | US | disclosed |