Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL358844 | 0.79 | ESR1 (0.40) | NPC1TP53RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL28526146 | 0.79 | ALDH1A1 (0.34) | NPC1TP53RAB9AKMT2AMAPT | |
| SCHEMBL358614 | 0.78 | CYP1A2 (0.48) | NPC1TP53RAB9ASMN1; SMN2TSHR | |
| SCHEMBL7123909 | 0.75 | HPGD (0.42) | NPC1RAB9ASMN1; SMN2KDM4EGABRP | |
| SCHEMBL358041 | 0.75 | NOTUM (0.34) | TSHRNOTUM | |
| SCHEMBL359663 | 0.75 | HRH3 (0.46) | — | |
| SCHEMBL28244471 | 0.72 | KIF11 (0.38) | NPC1RAB9ASMN1; SMN2KDM4ENPY5R | |
| SCHEMBL7929388 | 0.71 | NPC1 (0.60) | NPC1TP53RAB9ASMN1; SMN2TSHR | |
| SCHEMBL5344839 | 0.71 | CYP1A2 (0.34) | NPC1RAB9ASMN1; SMN2KMT2AMAPT | |
| SCHEMBL11080352 | 0.71 | MAPK1 (0.38) | TSHRHSD17B10KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104926628-B | A kind of synthetic method of benzil analog derivative | 浙江工业大学 | 2016-08-24 | — | — | CN | disclosed |
| CN-104926628-A | Method for synthesizing benzil derivative | UNIV ZHEJIANG TECHNOLOGY | 2015-09-23 | — | — | CN | disclosed |