SCHEMBL7929388

SCHEMBL7929388

Fc1ccc(-c2ccc(Cl)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.60
TP53 P04637 1/20 0.60
TSHR P16473 1/20 0.60
RAB9A P51151 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
HSD17B10 Q99714 1/20 0.60
CYP1A2 P05177 1/20 0.55
LMNA P02545 1/20 0.50
CYP2A6 P11509 1/20 0.50
AHR P35869 1/20 0.48
CNR1 P21554 1/20 0.46
KMT2A Q03164 1/20 0.46
NPY5R Q15761 1/20 0.44
BCL2L1 Q07817 1/20 0.44
BAD Q92934 1/20 0.44
ALOX5 P09917 1/20 0.44
MAPT P10636 3/20 0.43
TXN P10599 1/20 0.43
THRB P10828 1/20 0.43
ALDH1A1 P00352 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5776485 0.90
SCHEMBL7024646 0.90
SCHEMBL35226 0.90
SCHEMBL3821175 0.87
SCHEMBL2972168 0.87
Fluoride SCHEMBL21986315 0.87 LMNA (0.57) NPC1TP53TSHRRAB9ASMN1; SMN2
SCHEMBL28215 0.83 CYP1A2 (0.73) NPC1TP53TSHRRAB9AHSD17B10
SCHEMBL3952742 0.83 CYP1A2 (0.73) NPC1TP53TSHRRAB9AHSD17B10
SCHEMBL11165087 0.83 CYP1A2 (0.73) NPC1TP53TSHRRAB9AHSD17B10
SCHEMBL197346 0.83 BCL2L1 (0.55) NPC1RAB9ASMN1; SMN2BCL2L1BAD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120058445-A Method for generating aryl phenol compound by hydroxylation of uranium photocatalytic aryl fluorine compound and application of method 华东师范大学 2025-05-30 CN disclosed
WO-2025033611-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR ORGANIC LAYER 엘티소재주식회사 2025-02-13 WO disclosed
CN-119306707-A Novel compound and organic light emitting device using the same 株式会社LG化学 2025-01-14 CN disclosed
WO-2024219945-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2024-10-24 WO disclosed
WO-2017070536-A1 METHODS AND AGENTS FOR TREATING DISEASES ANGION BIOMEDICA CORP. (US) 2017-04-27 WO disclosed
US-6242654-B1 REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND MITSUI CHEMICALS, INC. (JP) 2001-06-05 US disclosed
EP-1013629-A1 Preparation process of fluorine subsituted aromatic compound Mitsui Chemicals, Inc. (JP) 2000-06-28 EP disclosed
EP-0334097-B1 PROCESS FOR THE PREPARATION OF 4,4'-DIHALOGENO-BISPHENYLS BAYER AG (DE) 1993-04-28 EP disclosed
US-4950817-A CATALYTIC HALOGENATION OF MONOHALO-BIPHENYL BAYER AKTIENGESELLSCHAFT (DE) 1990-08-21 US disclosed
EP-0334097-A2 Process for the preparation of 4,4'-Dihalogeno-bisphenyls BAYER AG (DE) 1989-09-27 EP disclosed