Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 6/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28089927 | 0.91 | LMNA (0.41) | LMNAS1PR5S1PR4S1PR1S1PR3 | |
| SCHEMBL28832903 | 0.72 | LMNA (0.47) | LMNAALDH1A1KDM4ETSHRHPGD | |
| Tert-Butylamine SCHEMBL28089805 | 0.69 | KCNH2 (0.49) | LMNAS1PR5S1PR4S1PR1S1PR3 | |
| SCHEMBL6944812 | 0.68 | KCNH2 (0.55) | S1PR5S1PR4S1PR1S1PR3ALDH1A1 | |
| SCHEMBL18896618 | 0.68 | S1PR5 (0.43) | LMNAS1PR5S1PR4S1PR1S1PR3 | |
| SCHEMBL18896629 | 0.68 | S1PR5 (0.43) | LMNAS1PR5S1PR4S1PR1S1PR3 | |
| SCHEMBL18896635 | 0.68 | LMNA (0.44) | LMNAS1PR5S1PR4S1PR1S1PR3 | |
| SCHEMBL396677 | 0.67 | KCNH2 (0.61) | S1PR5S1PR4S1PR1S1PR3KCNH2 | |
| SCHEMBL7735976 | 0.67 | LMNA (0.44) | LMNAALDH1A1KDM4ETSHRHPGD | |
| Hexadecane SCHEMBL28525033 | 0.66 | PLG (0.48) | LMNAS1PR5S1PR4S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103619838-B | Piperidinyl monocarboxylic acids as S1P1 receptor agonists | 生物计划公司 | 2016-08-24 | — | — | CN | disclosed |