Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | NEK2 | P51955 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28089804 | 0.91 | LMNA (0.40) | LMNAALDH1A1S1PR5KDM4EHPGD | |
| SCHEMBL28832903 | 0.74 | LMNA (0.47) | LMNAALDH1A1HSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL28089793 | 0.72 | ALDH1A1 (0.39) | ALDH1A1HSD17B10SMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL7735976 | 0.69 | LMNA (0.44) | LMNAALDH1A1HSD17B10KDM4EL3MBTL1 | |
| SCHEMBL14768473 | 0.67 | LMNA (0.51) | LMNAALDH1A1HSD17B10S1PR5SMN1; SMN2 | |
| Tert-Butylamine SCHEMBL28089928 | 0.67 | SMN1; SMN2 (0.54) | LMNAS1PR5SMN1; SMN2L3MBTL1S1PR4 | |
| SCHEMBL458560 | 0.66 | SMN1; SMN2 (0.61) | LMNAS1PR5SMN1; SMN2L3MBTL1S1PR4 | |
| SCHEMBL8237599 | 0.66 | LMNA (0.50) | LMNAALDH1A1HSD17B10SMN1; SMN2L3MBTL1 | |
| SCHEMBL855052 | 0.65 | SMN1; SMN2 (0.67) | LMNAALDH1A1HSD17B10S1PR5SMN1; SMN2 | |
| SCHEMBL4767761 | 0.65 | LMNA (0.53) | LMNAALDH1A1HSD17B10SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103619838-B | Piperidinyl monocarboxylic acids as S1P1 receptor agonists | 生物计划公司 | 2016-08-24 | — | — | CN | disclosed |