Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRE | P78334 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2692890 | 0.87 | NOTUM (0.42) | LMNAALDH1A1NOTUM | |
| SCHEMBL8150412 | 0.80 | SMN1; SMN2 (0.53) | KDM4ETSHRGAAL3MBTL1ALDH1A1 | |
| SCHEMBL28832903 | 0.79 | LMNA (0.47) | LMNAKDM4EUSP2HPGDNPSR1 | |
| SCHEMBL1256089 | 0.74 | MEN1 (0.61) | LMNANPSR1HSD17B10GAAL3MBTL1 | |
| SCHEMBL46774 | 0.73 | ALDH1A1 (0.55) | LMNAKDM4EUSP2HPGDNPSR1 | |
| SCHEMBL3097907 | 0.72 | LMNA (0.49) | LMNANPSR1HSD17B10GAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL641317 | 0.71 | ALDH1A1 (0.58) | LMNAKDM4EUSP2HPGDNPSR1 | |
| SCHEMBL3092846 | 0.71 | ALDH1A1 (0.53) | LMNAKDM4EUSP2HPGDNPSR1 | |
| Iodide SCHEMBL30988366 | 0.71 | ALDH1A1 (0.53) | LMNAKDM4EUSP2HPGDNPSR1 | |
| Water SCHEMBL5420438 | 0.71 | ALDH1A1 (0.53) | LMNAKDM4EUSP2HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410792-B1 | OBESITY DISEASES | BAYER CORPORATION | 2002-06-25 | — | — | US | disclosed |
| US-6048900-A | FOR TREATING EATING DISORDERS, INSULIN RESISTANT DIABETES, HYPERTENSION, HYPERLIPEMIA | BAYER CORPORATION (US) | 2000-04-11 | — | — | US | disclosed |