Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | TACR3 | P29371 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13241025 | 0.87 | ALDH1A1 (0.44) | ALDH1A1LMNAKMT2AMEN1L3MBTL1 | |
| SCHEMBL2487574 | 0.87 | ALDH1A1 (0.44) | ALDH1A1LMNAKMT2AMEN1L3MBTL1 | |
| SCHEMBL12497078 | 0.79 | PTGS2 (0.47) | LMNAKMT2AMEN1KDM4EPKM | |
| SCHEMBL1701115 | 0.78 | KDM4E (0.44) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL30059683 | 0.73 | ALDH1A1 (0.56) | ALDH1A1LMNAKMT2AMEN1MC4R | |
| SCHEMBL1274762 | 0.73 | ALDH1A1 (0.56) | ALDH1A1LMNAKMT2AMEN1MC4R | |
| SCHEMBL8410789 | 0.72 | CES2 (0.56) | ALDH1A1LMNAKMT2AMEN1MC4R | |
| SCHEMBL31612953 | 0.72 | KMT2A (0.50) | ALDH1A1LMNAKMT2AMEN1MC4R | |
| SCHEMBL7522990 | 0.72 | CES2 (0.56) | ALDH1A1LMNAKMT2AMEN1MC4R | |
| SCHEMBL8676087 | 0.72 | KMT2A (0.50) | ALDH1A1LMNAKMT2AMEN1MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102947300-B | Alkaloid amino ester derivative and pharmaceutical composition thereof | 奇斯药制品公司 | 2016-09-21 | — | — | CN | disclosed |