Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.50 |
| ▸ | CDK4 | P11802 | 3/20 | 0.50 |
| ▸ | CCND1 | P24385 | 3/20 | 0.50 |
| ▸ | PARP1 | P09874 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL542799 | 0.94 | CDK4 (0.55) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL29946446 | 0.94 | CDK4 (0.55) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| Benzene SCHEMBL29042456 | 0.92 | CDK4 (0.54) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| Biphenyl SCHEMBL29284827 | 0.88 | CDK4 (0.50) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9247956 | 0.88 | CDK4 (0.53) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| Phenanthroline SCHEMBL28213147 | 0.82 | KDM4E (0.61) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9394726 | 0.82 | LMNA (0.45) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL19988646 | 0.81 | NPC1 (0.53) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL21155426 | 0.79 | MAPT (0.56) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL3837922 | 0.77 | KIF11 (0.53) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103497211-B | Indoloquinoline derivant and its preparation method and application | 中国海洋大学 | 2016-07-20 | — | — | CN | disclosed |