SCHEMBL542799

SCHEMBL542799

c1cnc2c(c1)ccc1[nH]c3ccccc3c12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 3/20 0.55
CCND1 P24385 3/20 0.55
GABRA1 P14867 4/20 0.55
GABRG2 P18507 4/20 0.55
GABRB3 P28472 4/20 0.55
GABRA5 P31644 4/20 0.55
GABRA3 P34903 4/20 0.55
GABRA2 P47869 4/20 0.55
PARP1 P09874 3/20 0.51
KDM4E B2RXH2 3/20 0.50
MAPT P10636 3/20 0.50
LMNA P02545 2/20 0.50
TP53 P04637 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
GMNN O75496 1/20 0.50
HSP90AA1 P07900 1/20 0.50
MMP2 P08253 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
MMP9 P14780 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29946446 1.00 CDK4 (0.55) CDK4CCND1GABRA1GABRG2GABRB3
Benzene SCHEMBL29042456 0.98 CDK4 (0.54) CDK4CCND1GABRA1GABRG2GABRB3
Biphenyl SCHEMBL29284827 0.94 CDK4 (0.50) CDK4CCND1GABRA1GABRG2GABRB3
SCHEMBL28089903 0.94 GABRA1 (0.50) CDK4CCND1GABRA1GABRG2GABRB3
SCHEMBL9247956 0.93 CDK4 (0.53) CDK4CCND1GABRA1GABRG2GABRB3
Phenanthroline SCHEMBL28213147 0.87 KDM4E (0.61) CDK4CCND1GABRA1GABRG2GABRB3
SCHEMBL9394726 0.87 LMNA (0.45) CDK4CCND1GABRA1GABRG2GABRB3
SCHEMBL19988646 0.86 NPC1 (0.53) CDK4CCND1GABRA1GABRG2GABRB3
SCHEMBL21155426 0.84 MAPT (0.56) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL3837922 0.82 KIF11 (0.53) CDK4CCND1GABRA1GABRG2GABRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 315 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250228127-A1 ORGANIC LIGHT-EMITTING DEVICE AND APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2025-07-10 US claimed
CN-120192316-A Biphenyl indoloquinoline structural compound, preparation method and OLED device 成都维拓立柔性电子技术有限公司 2025-06-24 CN claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
US-12284859-B2 Organic light-emitting device and apparatus including the same SAMSUNG DISPLAY CO., LTD. (KR) 2025-04-22 US claimed
CN-119119031-A Process for preparing indoloquinoline derivatives 江苏师范大学 2024-12-13 CN claimed
CN-118239950-A Biphenyl indoloquinoline structural compound, preparation method and OLED device 成都维拓立柔性电子技术有限公司 2024-06-25 CN claimed
CN-116617226-A Application of novel indole quinoline derivative as enterovirus 71 inhibitor 湖北工业大学 2023-08-22 CN claimed
CN-114560859-B Indoloquinoline derivative and preparation method and application thereof 华中师范大学 2023-08-01 CN claimed
US-20230225144-A1 ORGANIC LIGHT-EMITTING DEVICE AND APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-13 US claimed
CN-113788828-B Preparation method and application of isofraxine analogue from norfloxacin to isofraxine analogue 黄河水利职业技术学院 2023-06-30 CN claimed
CN-103910723-A Method for synthesizing indoloquinoline derivatives through visible light catalysis CHINESE ACAD TECH INST PHYSICS 2014-07-09 CN claimed
CN-103497211-A Indoloquinoline derivative and preparation method and application thereof OCEAN UNIV CHINA 2014-01-08 CN claimed
CN-102924448-A Alkaloid cryptolepine analogue quindoline acid compound and preparation method UNIV BOHAI 2013-02-13 CN claimed
CN-102006773-A Formulations and devices for delivering compounds to arthropods and microorganisms within arthopods MEVLABS INC 2011-04-06 CN claimed
US-20100247485-A1 FORMULATIONS AND DEVICES FOR DELIVERING COMPOUNDS TO ARTHROPODS AND MICROORGANISMS WITHIN ARTHOPODS MEVLABS, INC. (US) 2010-09-30 US claimed
EP-2200428-A1 FORMULATIONS AND DEVICES FOR DELIVERING COMPOUNDS TO ARTHROPODS AND MICROORGANISMS WITHIN ARTHOPODS Mevlabs, Inc. (US) 2010-06-30 EP claimed
WO-2009032975-A1 FORMULATIONS AND DEVICES FOR DELIVERING COMPOUNDS TO ARTHROPODS AND MICROORGANISMS WITHIN ARTHOPODS MEVLABS, INC. (US) 2009-03-12 WO claimed
US-5128345-A CARCINOSTATIC COMPOSITION COMPRISING INDOLQUINOLINES MECT CORPORATION (JP) 1992-07-07 US claimed
CN-1036763-A The fused quinoline compounds, condense the method for acridine compound, the such compound of preparation and contain such compound control the cancer composition KANTO ISHI PHARMA CO LTD (JP) 1989-11-01 CN claimed
EP-0332190-A2 Condensed quinoline system compound, condensed acridine system compound, process for preparing the same, and carcinostatic composition containing the same MECT CORPORATION (JP) 1989-09-13 EP claimed