Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 5/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 5/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 5/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 7/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10002324 | 0.85 | PARP1 (0.42) | SYKDHODH | |
| SCHEMBL19657299 | 0.83 | SYK (0.43) | SYK | |
| SCHEMBL22050698 | 0.75 | F7 (0.44) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL30863595 | 0.75 | SYK (0.41) | SYKNOTUMHPGDCSNK2A1PIM3 | |
| SCHEMBL15132061 | 0.74 | CDK2 (0.35) | PIM3 | |
| SCHEMBL6724863 | 0.73 | PRKAG1 (0.40) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL14985857 | 0.72 | PDK2 (0.38) | — | |
| SCHEMBL9930734 | 0.72 | F7 (0.41) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL15126263 | 0.72 | MAPK1 (0.41) | — | |
| SCHEMBL26690258 | 0.71 | F7 (0.47) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103582644-B | Phthalazinone-Pyrrolopyrimidine Carboxamide Derivatives | 塔科达有限责任公司 | 2016-07-20 | — | — | CN | disclosed |