Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.41 |
| ▸ | HTR1A | P08908 | 4/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28089926 | 0.73 | CYP2D6 (0.39) | SLC6A2SLC6A4SLC6A3KDM4ECYP4F2 | |
| SCHEMBL13506327 | 0.70 | LMNA (0.56) | GRM2KDM4E | |
| SCHEMBL2701733 | 0.69 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3KDM4ECYP4F2 | |
| SCHEMBL3948951 | 0.68 | GRM2 (0.49) | GRM2KDM4E | |
| Hydrochloric Acid SCHEMBL6208767 | 0.68 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3KDM4ECYP4F2 | |
| SCHEMBL23112167 | 0.67 | ALDH1A1 (0.49) | GRM2KDM4E | |
| SCHEMBL1007343 | 0.67 | GRM2 (0.48) | GRM2KDM4E | |
| SCHEMBL30342289 | 0.67 | KMT2A (0.33) | SLC6A2SLC6A4SLC6A3KDM4ECYP4F2 | |
| SCHEMBL1007504 | 0.66 | GRM2 (0.43) | SLC6A2SLC6A4SLC6A3HTR1AGRM2 | |
| SCHEMBL28049599 | 0.66 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103619838-B | Piperidinyl monocarboxylic acids as S1P1 receptor agonists | 生物计划公司 | 2016-08-24 | — | — | CN | disclosed |