Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL891025 | 0.80 | POLB (0.33) | DAOHTR1A | |
| SCHEMBL25651305 | 0.74 | ALDH1A1 (0.47) | ALDH1A1HPGDMEN1KMT2ADAO | |
| SCHEMBL10061340 | 0.72 | HMBS (0.43) | ALDH1A1HPGDMEN1KMT2ANPC1 | |
| SCHEMBL28222880 | 0.70 | TSHR (0.38) | ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL891414 | 0.67 | — | — | |
| SCHEMBL9224370 | 0.67 | KDM4E (0.33) | ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL25422518 | 0.65 | — | — | |
| SCHEMBL12493019 | 0.65 | — | — | |
| SCHEMBL19007328 | 0.65 | — | — | |
| SCHEMBL28070945 | 0.65 | ALDH1A1 (0.33) | ALDH1A1HPGDMEN1KMT2ADAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104277004-B | Prepare method and its intermediate of pyridazinone compound | 住友化学株式会社 | 2016-08-24 | — | — | CN | disclosed |