SCHEMBL28090296

SCHEMBL28090296

CC=Cc1cccc(N2CCCCC2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT6 Q96LA8 1/20 0.47
ALDH1A1 P00352 4/20 0.44
KDM4E B2RXH2 3/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
GAA P10253 2/20 0.44
HPGD P15428 1/20 0.44
HSD17B10 Q99714 1/20 0.44
HDAC4 P56524 2/20 0.43
MEF2D Q14814 2/20 0.43
AGXT P21549 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
APP P05067 1/20 0.40
MAPT P10636 2/20 0.40
S100B P04271 2/20 0.39
TERT O14746 1/20 0.39
LMNA P02545 1/20 0.39
PKM P14618 1/20 0.39
ALOX15 P16050 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5610645 0.98 PRMT6 (0.45) PRMT6ALDH1A1KDM4EMEN1KMT2A
SCHEMBL28199225 0.91 ADRA2C (0.46) ALDH1A1GAAHDAC4SMN1; SMN2MAPT
SCHEMBL23048845 0.85 ADRA2C (0.57) ALDH1A1KDM4EMEN1KMT2AGAA
SCHEMBL14261396 0.83 MAPT (0.50) ALDH1A1KDM4EMEN1KMT2AHSD17B10
SCHEMBL27862064 0.82 PRMT6 (0.48) PRMT6ALDH1A1KDM4EMEN1KMT2A
SCHEMBL21558408 0.81 TRIM24 (0.41) ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2
SCHEMBL22917294 0.80 PRMT6 (0.42) PRMT6ALDH1A1KDM4EMEN1KMT2A
SCHEMBL27840550 0.80 AGXT (0.46) PRMT6ALDH1A1KDM4EMEN1KMT2A
SCHEMBL609136 0.79 PRMT6 (0.46) PRMT6ALDH1A1KDM4EMEN1KMT2A
SCHEMBL1418736 0.79 ALDH1A1 (0.61) PRMT6ALDH1A1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104045769-B Conjugated diene polymer, and the polymer composition containing the polymer 住友化学株式会社 2018-10-30 CN disclosed
CN-104098744-B Conjugated diene polymer, and the polymer composition containing the polymer 住友化学株式会社 2018-02-16 CN disclosed
CN-104045768-B Conjugated diene polymer, and the polymer composition containing the polymer 住友化学株式会社 2018-02-16 CN disclosed
CN-104334629-B Rubber composition for tire tread and pneumatic tire 住友橡胶工业株式会社 2016-08-24 CN disclosed