Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.45 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.45 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14005200 | 0.85 | EPHX2 (0.58) | HTTALDH1A1MAPK1L3MBTL1ELANE | |
| SCHEMBL28117958 | 0.83 | ALDH1A1 (0.49) | HTTALDH1A1MAPK1L3MBTL1HRH4 | |
| SCHEMBL3660419 | 0.82 | HTT (0.56) | HTTALDH1A1MAPK1L3MBTL1LMNA | |
| SCHEMBL316883 | 0.82 | CA1 (0.66) | HTTCA1CA2ALDH1A1MAPK1 | |
| SCHEMBL23518457 | 0.81 | ALDH1A1 (0.51) | HTTALDH1A1MAPK1L3MBTL1HRH4 | |
| SCHEMBL19733921 | 0.81 | ALDH1A1 (0.51) | HTTALDH1A1MAPK1L3MBTL1HRH4 | |
| SCHEMBL7301249 | 0.81 | ALDH1A1 (0.51) | HTTALDH1A1MAPK1L3MBTL1HRH4 | |
| SCHEMBL13323438 | 0.80 | ALDH1A1 (0.61) | HTTALDH1A1MAPK1L3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL17335911 | 0.80 | ALDH1A1 (0.50) | HTTALDH1A1MAPK1L3MBTL1HRH4 | |
| SCHEMBL7510972 | 0.80 | HTT (0.67) | HTTALDH1A1MAPK1PRSS1TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105792852-A | Glucose-responsive insulin conjugates | 默沙东公司 | 2016-07-20 | — | — | CN | disclosed |