Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 4/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13323438 | 0.95 | ALDH1A1 (0.61) | HTTALDH1A1MAPK1L3MBTL1LTA4H | |
| SCHEMBL7378770 | 0.89 | CA1 (0.58) | HTTALDH1A1MAPK1L3MBTL1LTA4H | |
| SCHEMBL24984042 | 0.89 | ALDH1A1 (0.54) | HTTALDH1A1MAPK1L3MBTL1LTA4H | |
| SCHEMBL18515898 | 0.87 | ALDH1A1 (0.53) | HTTALDH1A1MAPK1L3MBTL1LTA4H | |
| SCHEMBL17177605 | 0.87 | ALDH1A1 (0.53) | HTTALDH1A1MAPK1L3MBTL1LTA4H | |
| SCHEMBL16791126 | 0.87 | ALDH1A1 (0.53) | HTTALDH1A1MAPK1L3MBTL1LTA4H | |
| SCHEMBL4169984 | 0.87 | CCR6 (0.57) | HTTALDH1A1MAPK1L3MBTL1LMNA | |
| SCHEMBL24119984 | 0.87 | ALDH1A1 (0.56) | HTTALDH1A1MAPK1L3MBTL1LTA4H | |
| SCHEMBL1627692 | 0.86 | ALDH1A1 (0.51) | HTTALDH1A1MAPK1L3MBTL1LTA4H | |
| Hydrochloric Acid SCHEMBL27352426 | 0.85 | CCR6 (0.56) | HTTALDH1A1MAPK1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217621-B1 | INSULIN DERIVATIVE | NOVO NORDISK AS (DK) | 2015-04-22 | — | — | EP | disclosed |
| US-8710000-B2 | Insulin derivative | NOVO NORDISK A/S (DK) | 2014-04-29 | — | — | US | disclosed |
| US-20100279931-A1 | Insulin Derivative | NOVO NORDISK A/S | 2010-11-04 | — | — | US | disclosed |
| EP-2217621-A1 | INSULIN DERIVATIVE | Novo Nordisk A/S (DK) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009060071-A1 | INSULIN DERIVATIVE | NOVO NORDISK A/S (DK) | 2009-05-14 | — | — | WO | disclosed |
| EP-2058330-A1 | Insulin derivative | NOVO NORDISK A/S (DK) | 2009-05-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100279931-A1 | Insulin Derivative | IAPP, INSR, GPR119 | HTT 1328/4885ALDH1A1 3984/4885MAPK1 2316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.