SCHEMBL28117958

SCHEMBL28117958

CC(=O)NCC(=O)NCCC(=O)OCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.49
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
HPGD P15428 1/20 0.48
MAPK1 P28482 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
LMNA P02545 2/20 0.47
HTT P42858 1/20 0.46
HRH4 Q9H3N8 1/20 0.45
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
ABCC3 O15438 1/20 0.44
NR1I2 O75469 1/20 0.44
ABCB11 O95342 1/20 0.44
NR3C1 P04150 1/20 0.44
RARG P13631 1/20 0.44
CNR1 P21554 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24526798 0.90 ALDH1A1 (0.56) ALDH1A1MEN1KMT2AHPGDMAPK1
SCHEMBL19733921 0.84 ALDH1A1 (0.51) ALDH1A1MEN1KMT2AHPGDMAPK1
SCHEMBL5966244 0.84 ALDH1A1 (0.59) ALDH1A1MEN1KMT2AHPGDMAPK1
SCHEMBL28090334 0.83 HTT (0.52) ALDH1A1MEN1KMT2AMAPK1L3MBTL1
SCHEMBL23518513 0.83 SYK (0.52) ALDH1A1MEN1KMT2AMAPK1L3MBTL1
SCHEMBL29055947 0.82 SYK (0.51) ALDH1A1MEN1KMT2ALMNAHTT
SCHEMBL9876468 0.82 POLB (0.48) ALDH1A1MEN1KMT2AHPGDMAPK1
SCHEMBL9876521 0.82 HDAC3 (0.49) ALDH1A1MEN1KMT2AHPGDMAPK1
SCHEMBL23518457 0.81 ALDH1A1 (0.51) ALDH1A1MEN1KMT2AMAPK1L3MBTL1
SCHEMBL7301249 0.81 ALDH1A1 (0.51) ALDH1A1MEN1KMT2AMAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106397256-A Synthesis method of compound 3 (2-acetamido) -propionic acid for inhibiting melanin generation 新钰生技股份有限公司 2017-02-15 CN claimed