Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28090537 | 0.90 | KDM4E (0.71) | MAPTTHRBKDM4EALDH1A1HPGD | |
| SCHEMBL28090832 | 0.86 | ALDH1A1 (0.57) | MAPTTHRBKDM4EALDH1A1HPGD | |
| SCHEMBL28090837 | 0.86 | ALDH1A1 (0.57) | MAPTTHRBKDM4EALDH1A1HPGD | |
| SCHEMBL28090870 | 0.83 | KDM4E (0.55) | MAPTTHRBKDM4EALDH1A1HPGD | |
| SCHEMBL28090875 | 0.82 | ALDH1A1 (0.69) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL28090534 | 0.80 | ADORA2A (0.63) | MAPTTHRBKDM4EALDH1A1HPGD | |
| SCHEMBL28090518 | 0.77 | MAPT (0.54) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL13667898 | 0.76 | MAPT (0.57) | MAPTKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL28090523 | 0.75 | MAPT (0.44) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL1759145 | 0.75 | KDM4E (0.77) | MAPTTHRBKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187923-A | 2 aryl 4 aroyl triazole compounds and application thereof | 沈阳药科大学 | 2016-12-07 | — | — | CN | disclosed |