Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28090836 | 0.89 | HDAC1 (0.51) | KDM4EHDAC1MEN1KMT2ACNR2 | |
| SCHEMBL28090835 | 0.85 | HTT (0.47) | MAPTHTTHDAC1MEN1KMT2A | |
| SCHEMBL28090831 | 0.85 | MAPK14 (0.52) | MAPTLMNAKDM4ENPSR1HDAC1 | |
| SCHEMBL15577164 | 0.83 | RPA1 (0.49) | SMN1; SMN2HDAC1MEN1KMT2ANPC1 | |
| SCHEMBL28090834 | 0.82 | HDAC1 (0.49) | KDM4EHDAC1MEN1KMT2ANPC1 | |
| SCHEMBL28090559 | 0.82 | MAPK14 (0.55) | MAPTSMN1; SMN2LMNAKDM4EHTT | |
| SCHEMBL28832952 | 0.79 | ADORA2A (0.42) | MAPTSMN1; SMN2KDM4EHTTNPSR1 | |
| SCHEMBL14949012 | 0.78 | KMT2A (0.44) | MAPTSMN1; SMN2LMNAKDM4EHTT | |
| SCHEMBL28090536 | 0.76 | SMN1; SMN2 (0.50) | MAPTSMN1; SMN2HTTHDAC1MEN1 | |
| SCHEMBL28090599 | 0.75 | MAPT (0.58) | MAPTSMN1; SMN2LMNAKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187923-A | 2 aryl 4 aroyl triazole compounds and application thereof | 沈阳药科大学 | 2016-12-07 | — | — | CN | disclosed |